The virome of vector mosquitoes

Mosquitoes are the major vectors for arthropod-borne viruses (arboviruses) of medical importance. Aedes aegypti and A. albopictus are the most prolific and widespread mosquito vectors being responsible for global transmission of dengue, Zika and Chikungunya viruses. Characterizing the collection of viruses circulating in mosquitoes, the virome, has long been of special interest. In addition to arboviruses, mosquitoes carry insect specific viruses (ISVs) that do not directly infect vertebrates. Mounting evidence indicates that ISVs interact with arboviruses and may affect mosquito vector competence. Here, we review our current knowledge about the virome of vector mosquitoes and discuss the challenges for the field that may lead to novel strategies to prevent outbreaks of arboviruses.

Automated summary

Mosquitoes are major vectors for arboviruses of medical importance, with a virome in mosquitoes being of special interest. In addition to arboviruses, mosquitoes carry ISVs that may interact with arboviruses and impact mosquito vector competence. Research on the virome of vector mosquitoes may lead to novel strategies for preventing arbovirus outbreaks.