期刊
BMJ OPEN
卷 11, 期 9, 页码 -出版社
BMJ PUBLISHING GROUP
DOI: 10.1136/bmjopen-2020-045628
关键词
child & adolescent psychiatry; health economics; paediatric endocrinology
资金
- National Institute for Health Research (NIHR), Health Services and Delivery Research [17/51/19]
- National Institutes of Health Research (NIHR) [17/51/19] Funding Source: National Institutes of Health Research (NIHR)
This prospective cohort study aims to explore outcomes of children and young people referred to the UK GIDS in terms of gender identity, mental health, physical health, and quality of life, as well as investigate the impact of factors such as co-occurring autism and early social transition. Logistic regression models and appropriate regression models will be used to explore associations between explanatory variables and gender dysphoria. Subgroup analyses based on birth-assigned gender, age at referral, and co-occurring autistic traits will also be conducted. Findings from the study will be disseminated through peer-reviewed journals, conferences, and stakeholder events to inform clinical practice.
Introduction Gender identity development services (GIDS) worldwide have seen a significant increase in referrals in recent years. Many of these referrals consist of children and young people (CYP) who experience gender-related distress. This study aims to improve understanding of outcomes of CYP referred to the UK GIDS, specifically regarding gender identity, mental health, physical health and quality of life. The impact of factors such as co-occurring autism and early social transition on outcomes over time will be explored. Methods and analysis This is a prospective cohort study of CYP aged 3-14 years when referred to the UK GIDS. Eligible participants will be <= 14 years at the time their referral was accepted and will be on the waitlist for the service when baseline measures are completed. Children aged under 12 years will complete the measures in an interview format with a researcher, while young people aged 12 years and over and their parents/caregivers will complete online or paper-based questionnaires. Participants will complete follow-up measures 12 months and 24 months later. The final sample size is expected to be approximately 500. Logistic regression models will be used to explore associations between prespecified explanatory variables and gender dysphoria. Appropriate regression models will also be used to investigate explanatory variables for other outcomes. Subgroup analyses based on birth-assigned gender, age at referral and co-occurring autistic traits will be explored. Ethics and dissemination The study has been approved by the Health Research Authority and London - Hampstead Research Ethics Committee (reference: 19/LO/0857). The study findings will be published in peer-reviewed journals and presented at both conferences and stakeholder events. Findings will be used to inform clinical practice.
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