相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities
Carl M. Gay et al.
CANCER CELL (2021)
FDA Approval Summary: Lurbinectedin for the Treatment of Metastatic Small Cell Lung Cancer
Sonia Singh et al.
CLINICAL CANCER RESEARCH (2021)
Mechanisms of small cell lung cancer metastasis
Julie Ko et al.
EMBO MOLECULAR MEDICINE (2021)
Guanosine triphosphate links MYC-dependent metabolic and ribosome programs in small-cell lung cancer
Fang Huang et al.
JOURNAL OF CLINICAL INVESTIGATION (2021)
Comparison of the different mechanisms of cytotoxicity induced by checkpoint kinase I inhibitors when used as single agents or in combination with DNA damage
Nicholas J. H. Warren et al.
ONCOGENE (2020)
New Approaches to SCLC Therapy: From the Laboratory to the Clinic
John T. Poirier et al.
JOURNAL OF THORACIC ONCOLOGY (2020)
A shift in glutamine nitrogen metabolism contributes to the malignant progression of cancer
Manabu Kodama et al.
NATURE COMMUNICATIONS (2020)
Targeted Therapies and Biomarkers in Small Cell Lung Cancer
Hirokazu Taniguchi et al.
FRONTIERS IN ONCOLOGY (2020)
Cell-cycle-dependent phosphorylation of RRM1 ensures efficient DNA replication and regulates cancer vulnerability to ATR inhibition
Zhen Shu et al.
ONCOGENE (2020)
Single-cell analyses reveal increased intratumoral heterogeneity after the onset of therapy resistance in small-cell lung cancer
C. Allison Stewart et al.
NATURE CANCER (2020)
Schlafen 11 (SLFN11), a restriction factor for replicative stress induced by DNA-targeting anti-cancer therapies
Junko Murai et al.
PHARMACOLOGY & THERAPEUTICS (2019)
De novo dNTP production is essential for normal postnatal murine heart development
Phong Tran et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Acetylation regulates ribonucleotide reductase activity and cancer cell growth
Guo Chen et al.
NATURE COMMUNICATIONS (2019)
Extraction of Aqueous Metabolites from Cultured Adherent Cells for Metabolomic Analysis by Capillary Electrophoresis-Mass Spectrometry
Ami Maruyama et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2019)
The mitochondrial deoxyguanosine kinase is required for cancer cell stemness in lung adenocarcinoma
Shengchen Lin et al.
EMBO MOLECULAR MEDICINE (2019)
Deoxyribonucleotide salvage falls short in whole animals
Christopher K. Mathews
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Metabolomics Platform with Capillary Electrophoresis Coupled with High-Resolution Mass Spectrometry for Plasma Analysis
Kazunori Sasaki et al.
ANALYTICAL CHEMISTRY (2019)
Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data
Charles M. Rudin et al.
NATURE REVIEWS CANCER (2019)
Improved LC/MS Methods for the Analysis of Metal-Sensitive Analytes Using Medronic Acid as a Mobile Phase Additive
Jordy J. Hsiao et al.
ANALYTICAL CHEMISTRY (2018)
Metabolic Determinants of Sensitivity to Phosphatidylinositol 3-Kinase Pathway Inhibitor in Small-Cell Lung Carcinoma
Hideki Makinoshima et al.
CANCER RESEARCH (2018)
Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers
Fang Huang et al.
CELL METABOLISM (2018)
Small-cell lung cancer: what we know, what we need to know and the path forward
Adi F. Gazdar et al.
NATURE REVIEWS CANCER (2017)
Ribonucleotide Reductase Catalytic Subunit M1 (RRM1) as a Novel Therapeutic Target in Multiple Myeloma
Morihiko Sagawa et al.
CLINICAL CANCER RESEARCH (2017)
Resistance to PARP inhibitors by SLFN11 inactivation can be overcome by ATR inhibition
Junko Murai et al.
ONCOTARGET (2016)
Potent effect of adenoviral vector expressing short hairpin RNA targeting ribonucleotide reductase large subunit M1 on cell viability and chemotherapeutic sensitivity to gemcitabine in non-small cell lung cancer cells
Yoshimasa Tokunaga et al.
EUROPEAN JOURNAL OF CANCER (2015)
Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma
Hideki Makinoshima et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Assessment of ABT-263 activity across a cancer cell line collection leads to a potent combination therapy for small-cell lung cancer
Anthony C. Faber et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Ribonucleotide reductase and cancer: biological mechanisms and targeted therapies
Y. Aye et al.
ONCOGENE (2015)
RRM1 maintains centrosomal integrity via CHK1 and CDK1 signaling during replication stress
Su-Hyeon Kim et al.
CANCER LETTERS (2014)
Epidermal Growth Factor Receptor ( EGFR) Signaling Regulates Global Metabolic Pathways in EGFR-mutated Lung Adenocarcinoma
Hideki Makinoshima et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Cellular regulation of ribonucleotide reductase in eukaryotes
Estrella Guarino et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2014)
Identification of a lung adenocarcinoma cell line with CCDC6-RET fusion gene and the effect of RET inhibitors in vitro and in vivo
Makito Suzuki et al.
CANCER SCIENCE (2013)
PTPRZ1 regulates calmodulin phosphorylation and tumor progression in small-cell lung carcinoma
Hideki Makinoshima et al.
BMC CANCER (2012)
Silencing of ribonucleotide reductase subunit M1 potentiates the antitumor activity of gemcitabine in resistant cancer cells
Piyanuch Wonganan et al.
CANCER BIOLOGY & THERAPY (2012)
Cyclin F-Mediated Degradation of Ribonucleotide Reductase M2 Controls Genome Integrity and DNA Repair
Vincenzo D'Angiolella et al.
CELL (2012)
Update on small cell carcinoma and its differentiation from squamous cell carcinoma and other non-small cell carcinomas
William D. Travis
MODERN PATHOLOGY (2012)
The potential of exploiting DNA-repair defects for optimizing lung cancer treatment
Sophie Postel-Vinay et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2012)
Proteomic Profiling Identifies Dysregulated Pathways in Small Cell Lung Cancer and Novel Therapeutic Targets Including PARP1
Lauren Averett Byers et al.
CANCER DISCOVERY (2012)
Effect of Three Types of Mixed Anesthetic Agents Alternate to Ketamine in Mice
Sumiko KAWAI et al.
EXPERIMENTAL ANIMALS (2011)
Features of Potentially Predictive Biomarkers of Chemotherapeutic Efficacy in Small Cell Lung Cancer
Alberto A. Chiappori et al.
JOURNAL OF THORACIC ONCOLOGY (2010)
Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles
Masahiro Sugimoto et al.
METABOLOMICS (2010)
Highly mutagenic and severely imbalanced dNTP pools can escape detection by the S-phase checkpoint
Dinesh Kumar et al.
NUCLEIC ACIDS RESEARCH (2010)
Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research
Carol Kilkenny et al.
PLOS BIOLOGY (2010)
Excision repair cross complementing-1 and topoisomerase IIα gene expression in small-cell lung cancer patients treated with platinum and etoposide -: A retrospective study
Paolo Ceppi et al.
JOURNAL OF THORACIC ONCOLOGY (2008)
mRNA expression of RRM1, ERCC1 and ERCC2 is not associated with chemosensitivity to cisplatin, carboplatin and gemcitabine in human lung cancer cell lines
Junichi Shimizu et al.
RESPIROLOGY (2008)
DNA precursor metabolism and genomic stability
Christopher K. Mathews
FASEB JOURNAL (2006)
Regulation of mammalian ribonucleotide reduction and dNTP pools after DNA damage and in resting cells
P Håkansson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
RRM1-induced metastasis suppression through PTEN-regulated pathways
A Gautam et al.
ONCOGENE (2003)
Apoptosis and lung cancer: A review
N Shivapurkar et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2003)