4.7 Article

High-throughput human primary cell-based airway model for evaluating influenza, coronavirus, or other respiratory viruses in vitro

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics

Christoph Muus et al.

Summary: Our study reveals that cell-type-specific expression patterns of ACE2, TMPRSS2, and CTSL are associated with the pathogenesis of COVID-19. Factors such as age, sex, and smoking status are linked to the expression of viral entry genes in respiratory cell populations, suggesting potential therapeutic targets for intervention. The integrated analysis of single-cell and single-nucleus transcriptomics studies highlights coexpression patterns of SARS-CoV-2 viral entry genes across different human tissues.

NATURE MEDICINE (2021)

Article Biochemical Research Methods

High-throughput organ-on-chip platform with integrated programmable fluid flow and real-time sensing for complex tissue models in drug development workflows†

H. Azizgolshani et al.

Summary: Drug development lacks predictive and human-relevant in vitro models. The Organ-on-chip (OOC) technology provides advanced culture capabilities to generate human-based tissue in vitro, but faces challenges in throughput and compatibility. This study presents an OOC platform with advanced culture capabilities supporting multiple human tissue models for drug screening and gene expression analysis.

LAB ON A CHIP (2021)

Editorial Material Medicine, General & Internal

Coronavirus Infections-More Than Just the Common Cold

Catharine I. Paules et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

Editorial Material Medicine, General & Internal

Nasal ACE2 Levels and COVID-19 in Children

Ankit B. Patel et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

Article Multidisciplinary Sciences

Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells

Shutoku Matsuyama et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Medicine, General & Internal

Compassionate Use of Remdesivir for Patients with Severe Covid-19

J. Grein et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Biotechnology & Applied Microbiology

SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology

Natacha S. Ogando et al.

JOURNAL OF GENERAL VIROLOGY (2020)

Article Biochemistry & Molecular Biology

The protein expression profile of ACE2 in human tissues

Feria Hikmet et al.

MOLECULAR SYSTEMS BIOLOGY (2020)

Review Multidisciplinary Sciences

SARS-CoV-2 vaccines in development

Florian Krammer

NATURE (2020)

Article Multidisciplinary Sciences

Type 2 and interferon inflammation regulate SARS-CoV-2 entry factor expression in the airway epithelium

Satria P. Sajuthi et al.

NATURE COMMUNICATIONS (2020)

Article Multidisciplinary Sciences

ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs

Ivan T. Lee et al.

NATURE COMMUNICATIONS (2020)

Article Virology

Baloxavir marboxil: the new influenza drug on the market

Ryan O'Hanlon et al.

CURRENT OPINION IN VIROLOGY (2019)

Article Biochemistry & Molecular Biology

Structural basis for human coronavirus attachment to sialic acid receptors

M. Alejandra Tortorici et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2019)

Review Chemistry, Analytical

Recent Advances in Body-on-a-Chip Systems

Jong Hwan Sung et al.

ANALYTICAL CHEMISTRY (2019)

Review Immunology

Influenza Virus: Dealing with a Drifting and Shifting Pathogen

Hyunsuh Kim et al.

VIRAL IMMUNOLOGY (2018)

Article Medicine, General & Internal

Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents

Frederick G. Hayden et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Biology

Expansion of Airway Basal Cells and Generation of Polarized Epithelium

Hannah Levardon et al.

BIO-PROTOCOL (2018)

Article Multidisciplinary Sciences

Flexible integration of free-standing nanowires into silicon photonics

Bigeng Chen et al.

NATURE COMMUNICATIONS (2017)

Article Cell & Tissue Engineering

Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells

Hongmei Mou et al.

CELL STEM CELL (2016)

Article Immunology

Long-term survival of influenza virus infected club cells drives immunopathology

Nicholas S. Heaton et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2014)

Review Biochemical Research Methods

Animal models for influenza virus pathogenesis, transmission, and immunology

Rajagowthamee R. Thangavel et al.

JOURNAL OF IMMUNOLOGICAL METHODS (2014)

Article Multidisciplinary Sciences

Genomic responses in mouse models poorly mimic human inflammatory diseases

Junhee Seok et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Reconstituting Organ-Level Lung Functions on a Chip

Dongeun Huh et al.

SCIENCE (2010)

Article Immunology

Viral Loads and Duration of Viral Shedding in Adult Patients Hospitalized with Influenza

Nelson Lee et al.

JOURNAL OF INFECTIOUS DISEASES (2009)

Article Biochemical Research Methods

Human airway epithelial cell culture to identify new respiratory viruses: Coronavirus NL63 as a model

Bridget S. Banach et al.

JOURNAL OF VIROLOGICAL METHODS (2009)

Article Virology

Plaque assay for human coronavirus NL63 using human colon carcinoma cells

Petra Herzog et al.

VIROLOGY JOURNAL (2008)

Article Immunology

1918 influenza: the mother of all pandemics

JK Taubenberger et al.

EMERGING INFECTIOUS DISEASES (2006)

Article Multidisciplinary Sciences

Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry

H Hofmann et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)