4.7 Article

Ecological plasticity to ions concentration determines genetic response and dominance of Anopheles coluzzii larvae in urban coastal habitats of Central Africa

期刊

SCIENTIFIC REPORTS
卷 11, 期 1, 页码 -

出版社

NATURE PORTFOLIO
DOI: 10.1038/s41598-021-94258-6

关键词

-

资金

  1. Agence Universitaire de la Francophonie (AUF)
  2. Institut de Recherche pour le Developpement (IRD)
  3. Centre International de Recherches Medicales de Franceville (CIRMF)
  4. AUF scholarship
  5. CIRMF scholarship

向作者/读者索取更多资源

The study found that Anopheles coluzzii exhibits ecological plasticity to breed in diverse aquatic conditions, with a predominance in breeding sites rich in ions. Additionally, gene expression patterns were comparable between urban and rural habitats, indicating a broad response to ions concentrations of various origins. This suggests that Anopheles coluzzii has a plastic response to occupy both coastal and urban habitats, which has important implications for malaria control efforts amidst rapid urban expansion in Africa in the near future.
In Central Africa, the malaria vector Anopheles coluzzii is predominant in urban and coastal habitats. However, little is known about the environmental factors that may be involved in this process. Here, we performed an analysis of 28 physicochemical characteristics of 59 breeding sites across 5 urban and rural sites in coastal areas of Central Africa. We then modelled the relative frequency of An. coluzzii larvae to these physicochemical parameters in order to investigate environmental patterns. Then, we assessed the expression variation of 10 candidate genes in An. coluzzii, previously incriminated with insecticide resistance and osmoregulation in urban settings. Our results confirmed the ecological plasticity of An. coluzzii larvae to breed in a large range of aquatic conditions and its predominance in breeding sites rich in ions. Gene expression patterns were comparable between urban and rural habitats, suggesting a broad response to ions concentrations of whatever origin. Altogether, An. coluzzii exhibits a plastic response to occupy both coastal and urban habitats. This entails important consequences for malaria control in the context of the rapid urban expansion in Africa in the coming years.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据