4.7 Article

Constructing graphs from genetic encodings

期刊

SCIENTIFIC REPORTS
卷 11, 期 1, 页码 -

出版社

NATURE PORTFOLIO
DOI: 10.1038/s41598-021-92577-2

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资金

  1. NIH NIGMS [T32 GM008313]
  2. Templeton World Charity Foundation [TWCF0268]
  3. Hungarian National Research, Development, and Innovation Office [GINOP-2.3.2-15-2016-00057]

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This passage discusses a method of network connection based on identity-dependent compatibility rules, deriving from genetic principles to generate specific topologies and various network structures. It also explores the characteristics of Random Genetic networks and their behavior under targeted attacks, serving as a relevant null-model for social and biological systems.
Our understanding of real-world connected systems has benefited from studying their evolution, from random wirings and rewirings to growth-dependent topologies. Long overlooked in this search has been the role of the innate: networks that connect based on identity-dependent compatibility rules. Inspired by the genetic principles that guide brain connectivity, we derive a network encoding process that can utilize wiring rules to reproducibly generate specific topologies. To illustrate the representational power of this approach, we propose stochastic and deterministic processes for generating a wide range of network topologies. Specifically, we detail network heuristics that generate structured graphs, such as feed-forward and hierarchical networks. In addition, we characterize a Random Genetic (RG) family of networks, which, like Erdos-Renyi graphs, display critical phase transitions, however their modular underpinnings lead to markedly different behaviors under targeted attacks. The proposed framework provides a relevant null-model for social and biological systems, where diverse metrics of identity underpin a node's preferred connectivity.

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