期刊
NUTRIENTS
卷 13, 期 9, 页码 -出版社
MDPI
DOI: 10.3390/nu13093149
关键词
survivorship; cancer; nutritional epidemiology; nutrition impact symptoms
资金
- NIH/NCI [P50CA097248]
- USDA-NIFA Hatch Project [1011487]
- Health Policy Research Scholars Program at the Robert Wood Johnson Foundation
- NCI Cancer Prevention and Control Training Grant [5T32CA09314-17]
- [T32CA090314]
This study evaluated the impact of four a priori-defined diet quality indices on nutrition impact symptoms (NIS) in patients with head and neck squamous cell carcinoma (HNSCC) 1 year postdiagnosis. It was found that higher adherence to the aMED and DASH diet quality indices before treatment may help reduce NIS burden at 1-year postdiagnosis.
Dietary intake is understood to contribute to nutrition impact symptoms (NIS) in patients with head and neck squamous cell carcinoma (HNSCC). The purpose of this study was to evaluate the performance of four a priori-defined diet quality indices on the presence of NIS 1 year following diagnosis using data on 323 participants from the University of Michigan Head and Neck Specialized Program of Research Excellence (UM-SPORE). Pretreatment dietary intake was measured before treatment initiation using a food frequency questionnaire. NIS were measured along seven subdomains. Multivariable binary logistic regression models were constructed to evaluate relationships between pretreatment scores on a priori-defined diet quality indices (AHEI-2010, aMED, DASH, and a low-carbohydrate score) and the presence of individual symptoms in addition to a composite symptom summary score 1-year postdiagnosis. There were several significant associations between different indices and individual NIS. For the symptom summary score, there were significant inverse associations observed for aMED (ORQ5-Q1: 0.36, 95% CI: 0.14-0.88, p(trend) = 0.04) and DASH (ORQ5-Q1: 0.38, 95% CI: 0.15-0.91, p(trend) = 0.02) and the presence of NIS 1-year postdiagnosis. Higher adherence to the aMED and DASH diet quality indices before treatment may reduce NIS burden at 1-year postdiagnosis.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据