期刊
MATERIALS
卷 14, 期 14, 页码 -出版社
MDPI
DOI: 10.3390/ma14143813
关键词
hydroxyapatite; dental decay; demineralization; remineralization; bioactive glass
类别
资金
- NIH-NIDCR [R01 DE025001]
- Romanian NUCLEU LAPLAS VI program [16N/2019, PN-III-P2-2.1-PED-2019-2949]
The experimental results suggest that toothpaste containing NovaMin has a strong potential for remineralization, which can effectively promote the repair and remineralization of teeth.
Tooth decay is a prevalent disease that initiates when the oral pH becomes acidic. Fluoride and/or bioactive glass (NovaMin) were used to regenerate/repair teeth that had been decalcified. In this present study, we investigated the effect of fluoride and/or bioactive glass (NovaMin) on remineralization of hydroxyapatite (HA) discs, which mimic the enamel surface of natural teeth. HA discs were etched with phosphoric acid and treated with one of the following toothpastes: (1) Sensodyne toothpaste with fluoride; (2) Sensodyne toothpaste with fluoride and bioactive glass (NovaMin); (3) Tom's toothpaste without fluoride or bioactive glass (NovaMin); and (4) Tom's toothpaste with bioactive glass (NovaMin). The toothpastes were applied on the etched discs for two minutes, once a day for 15 days. Scanning electron microscopy (SEM) was used to analyze surface morphologies and X-ray photoelectron spectroscopy (XPS) was used to analyze surface compositions. Tom's toothpaste with only NovaMin demonstrated the most remineralization potential compared with the other groups. In conclusion, incorporating bioactive glass (NovaMin) into toothpastes could benefit the repair and remineralization of teeth.
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