Botulinum toxin type A therapy for bilateral focal neuropathic pruritus in multiple sclerosis: a case report

Neuropathic pruritus is a form of chronic itch that occurs in the presence of direct damage to the nervous system. It tends to be severe, disabling, and difficult to treat. Usual antipruritic medications are largely ineffective and there is no consensus regarding the treatment approach. The authors report a case of a 58-year-old man with primary progressive multiple sclerosis and a history of unsatisfactory management of severe bilateral focal pruritus. Significant symptom relief was attained after local intradermal injections of botulinum toxin type A.

Automated summary

Neuropathic pruritus is a chronic itch that occurs due to direct damage to the nervous system and is often difficult to treat. In this case, a significant relief of symptoms was achieved through local intradermal injections of botulinum toxin type A in a patient with primary progressive multiple sclerosis and severe bilateral focal pruritus.