相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Molecular genetic framework underlying pulmonary arterial hypertension
Laura Southgate et al.
NATURE REVIEWS CARDIOLOGY (2020)
The u-series: A separable decomposition for electrostatics computation with improved accuracy
Cristian Predescu et al.
JOURNAL OF CHEMICAL PHYSICS (2020)
Development of a Force Field for the Simulation of Single-Chain Proteins and Protein-Protein Complexes
Stefano Piana et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2020)
Bone morphogenetic protein receptor signal transduction in human disease
Maria Catalina Gomez-Puerto et al.
JOURNAL OF PATHOLOGY (2019)
Atomic-level characterization of protein-protein association
Albert C. Pan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments
Glenn R. Masson et al.
NATURE METHODS (2019)
Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
Dorothee Liebschner et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2019)
The PRIDE database and related tools and resources in 2019: improving support for quantification data
Yasset Perez-Riverol et al.
NUCLEIC ACIDS RESEARCH (2019)
Structural consequences of BMPR2 kinase domain mutations causing pulmonary arterial hypertension
Apirat Chaikuad et al.
SCIENTIFIC REPORTS (2019)
Improvements to the APBS biomolecular solvation software suite
Elizabeth Jurrus et al.
PROTEIN SCIENCE (2018)
A novel piperidine identified by stem cell-based screening attenuates pulmonary arterial hypertension by regulating BMP2 and PTGS2 levels
Yanjiang Xing et al.
EUROPEAN RESPIRATORY JOURNAL (2018)
A heterodimer formed by bone morphogenetic protein 9 (BMP9) and BMP10 provides most BMP biological activity in plasma
Emmanuelle Tillet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Calmodulin-induced Conformational Control and Allostery Underlying Neuronal Nitric Oxide Synthase Activation
Quinlin M. Hanson et al.
JOURNAL OF MOLECULAR BIOLOGY (2018)
Developing a molecular dynamics force field for both folded and disordered protein states
Paul Robustelli et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
BMP-2/7 heterodimer strongly induces bone regeneration in the absence of increased soft tissue inflammation
Takashi Kaito et al.
SPINE JOURNAL (2018)
Treatment with low-dose tacrolimus inhibits bleeding complications in a patient with hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension
N. Sommer et al.
PULMONARY CIRCULATION (2018)
The activin-βA/BMP-2 chimera AB204 is a strong stimulator of adipogenesis
Meejung Kim et al.
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2017)
Regulation of TGF-β Family Signaling by Inhibitory Smads
Keiji Miyazawa et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2017)
Tacrolimus rescues the signaling and gene expression signature of endothelial ALK1 loss-of-function and improves HHT vascular pathology
Santiago Ruiz et al.
HUMAN MOLECULAR GENETICS (2017)
PATTERNING AND AXIS FORMATION Heterodimers reign in the embryo
Benjamin Tajer et al.
ELIFE (2017)
Structural insights into BMP receptors: Specificity, activation and inhibition
David Yadin et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2016)
Common mutations in ALK2/ACVR1, a multi-faceted receptor, have roles in distinct pediatric musculoskeletal and neural orphan disorders
Maurizio Pacifici et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2016)
Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome
Risa Kashima et al.
SCIENCE SIGNALING (2016)
Structural Biology and Evolution of the TGF-β Family
Andrew P. Hinck et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)
Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome
Risa Kashima et al.
SCIENCE SIGNALING (2016)
BMPR2 mutations and survival in pulmonary arterial hypertension: an individual participant data meta-analysis
Jonathan D. W. Evans et al.
LANCET RESPIRATORY MEDICINE (2016)
Pulmonary Arterial Hypertension: A Current Perspective on Established and Emerging Molecular Genetic Defects
Rajiv D. Machado et al.
HUMAN MUTATION (2015)
Water Dispersion Interactions Strongly Influence Simulated Structural Properties of Disordered Protein States
Stefano Piana et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2015)
ACVR1R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A
Sarah J. Hatsell et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
ACVR1 Mutations in DIPG: Lessons Learned from FOP
Kathryn R. Taylor et al.
CANCER RESEARCH (2014)
Architectures of Whole-Module and Bimodular Proteins from the 6-Deoxyerythronolide B Synthase
Andrea L. Edwards et al.
JOURNAL OF MOLECULAR BIOLOGY (2014)
Molecular basis for pseudokinase-dependent autoinhibition of JAK2 tyrosine kinase
Yibing Shan et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2014)
How good are my data and what is the resolution?
Philip R. Evans et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2013)
Accurate and efficient integration for molecular dynamics simulations at constant temperature and pressure
Ross A. Lippert et al.
JOURNAL OF CHEMICAL PHYSICS (2013)
Constitutively Active ALK2 Receptor Mutants Require Type II Receptor Cooperation
Jana Bagarova et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
A New Class of Small Molecule Inhibitor of BMP Signaling
Caroline E. Sanvitale et al.
PLOS ONE (2013)
Oligomeric interactions of TGF-β and BMP receptors
Marcelo Ehrlich et al.
FEBS LETTERS (2012)
Promiscuity and specificity in BMP receptor activation
Thomas D. Mueller et al.
FEBS LETTERS (2012)
New developments in the ATSAS program package for small-angle scattering data analysis
Maxim V. Petoukhov et al.
JOURNAL OF APPLIED CRYSTALLOGRAPHY (2012)
SMAD versus Non-SMAD Signaling Is Determined by Lateral Mobility of Bone Morphogenetic Protein (BMP) Receptors
Asja Guzman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Structure of the Bone Morphogenetic Protein Receptor ALK2 and Implications for Fibrodysplasia Ossificans Progressiva
Apirat Chaikuad et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
HDX Workbench: Software for the Analysis of H/D Exchange MS Data
Bruce D. Pascal et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2012)
TGFβ signalling in context
Joan Massague
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Overview of the CCP4 suite and current developments
Martyn D. Winn et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2011)
Bone Morphogenetic Proteins: A critical review
Beth Bragdon et al.
CELLULAR SIGNALLING (2011)
How Does a Drug Molecule Find Its Target Binding Site?
Yibing Shan et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Designer TGFβ Superfamily Ligands with Diversified Functionality
George P. Allendorph et al.
PLOS ONE (2011)
XDS
Wolfgang Kabsch
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
Quantitative analysis of TGFBR2 mutations in Marfan-syndrome-related disorders suggests a correlation between phenotypic severity and Smad signaling activity
Daniel Horbelt et al.
JOURNAL OF CELL SCIENCE (2010)
Improved side-chain torsion potentials for the Amber ff99SB protein force field
Kresten Lindorff-Larsen et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2010)
Optimized Molecular Dynamics Force Fields Applied to the Helix-Coil Transition of Polypeptides
Robert B. Best et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2009)
Stoichiometric imbalance in the receptor complex contributes to dysfunctional BMPR-II mediated signalling in pulmonary arterial hypertension
M. Talat Nasim et al.
HUMAN MOLECULAR GENETICS (2008)
Phaser crystallographic software
Airlie J. McCoy et al.
JOURNAL OF APPLIED CRYSTALLOGRAPHY (2007)
Comparison of multiple amber force fields and development of improved protein backbone parameters
Viktor Hornak et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2006)
Aneurysm syndromes caused by mutations in the TGF-β receptor
Bart L. Loeys et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor
Xuewu Zhang et al.
CELL (2006)
The structural basis for autoinhibition of FLT3 by the juxtamembrane domain
J Griffith et al.
MOLECULAR CELL (2004)
Molecular recognition in bone morphogenetic protein (BMP)/receptor interaction
W Sebald et al.
BIOLOGICAL CHEMISTRY (2004)
Juxtamembrane autoinhibition in receptor tyrosine kinases
SR Hubbard
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Molecular and functional analysis identifies ALK-1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasia
RE Harrison et al.
JOURNAL OF MEDICAL GENETICS (2003)
Mutations in bone morphogenetic protein receptor 1B cause brachydactyly type A2
K Lehmann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
PRIMUS:: a Windows PC-based system for small-angle scattering data analysis
PV Konarev et al.
JOURNAL OF APPLIED CRYSTALLOGRAPHY (2003)
Uniqueness of ab initio shape determination in small-angle scattering
VV Volkov et al.
JOURNAL OF APPLIED CRYSTALLOGRAPHY (2003)
Disease-associated mutations in conserved residues of ALK-1 kinase domain
SA Abdalla et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2003)
Structural basis for peptide binding in protein kinase A - Role of glutamic acid 203 and tyrosine 204 in the peptide-positioning loop
MJ Moore et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Functional heterogeneity of bone morphogenetic protein receptor-II mutants found in patients with primary pulmonary hypertension
A Nishihara et al.
MOLECULAR BIOLOGY OF THE CELL (2002)
Genetics of pulmonary hypertension: from bench to bedside
M Humbert et al.
EUROPEAN RESPIRATORY JOURNAL (2002)
Functional analysis of bone morphogenetic protein type II receptor mutations underlying primary pulmonary hypertension
N Rudarakanchana et al.
HUMAN MOLECULAR GENETICS (2002)
The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways
A Nohe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Structural basis for autoinhibition of the EphB2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region
LE Wybenga-Groot et al.
CELL (2001)
The TGFβ receptor activation process:: An inhibitor- to substrate-binding switch
M Huse et al.
MOLECULAR CELL (2001)
Transforming growth factor β receptor signaling and endocytosis are linked through a COOH terminal activation motif in the type I receptor
N Garamszegi et al.
MOLECULAR BIOLOGY OF THE CELL (2001)
Automated matching of high- and low-resolution structural models
MB Kozin et al.
JOURNAL OF APPLIED CRYSTALLOGRAPHY (2001)
BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension
RD Machado et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2001)
Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-β family
JR Thomson et al.
JOURNAL OF MEDICAL GENETICS (2000)
Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene
ZM Deng et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2000)
Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension
KB Lane et al.
NATURE GENETICS (2000)
Bone morphogenetic protein receptor complexes on the surface of live cells: A new oligomerization mode for serine/threonine kinase receptors
L Gilboa et al.
MOLECULAR BIOLOGY OF THE CELL (2000)