Microglia have a grip on brain microvasculature

Microglia are brain resident immune cells with multiple functions. However, little is known about microglia-vascular interactions. In a recent paper published in Nature Communications, Bisht et al. identify a signalling mechanism that attracts and maintains microglia at the capillary wall. Moreover, they show that microglia regulate capillary vascular tone, playing a more significant role in blood flow regulation than previously thought.

Automated summary

Microglia play a crucial role in regulating capillary vascular tone and blood flow, with a recently identified signaling mechanism attracting and maintaining them at the capillary wall.