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Tai-Yuan Yu et al.
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Rekha Rai et al.
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Rajashree A. Deshpande et al.
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Yaqi Liu et al.
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Julyun Oh et al.
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Lili Pan et al.
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Hannah Kaizer et al.
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Atsushi Shibata et al.
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Elda Cannavo et al.
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Tianlai Shi et al.
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The fission yeast MRN complex tethers dysfunctional telomeres for NHEJ repair
Clara Correia Reis et al.
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Marina Martina et al.
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Anticheckpoint pathways at telomeres in yeast
Cyril Ribeyre et al.
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Katja Lammens et al.
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Yong Chen et al.
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Virginie Faure et al.
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Reduced Rif2 and lack of Mec1 target short telomeres for elongation rather than double-strand break repair
Jean S. McGee et al.
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Diego Bonetti et al.
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Plasticity of telomere maintenance mechanisms in yeast
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Yunmei Ma et al.
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Cell Cycle-Dependent Role of MRN at Dysfunctional Telomeres: ATM Signaling-Dependent Induction of Nonhomologous End Joining (NHEJ) in G1 and Resection-Mediated Inhibition of NHEJ in G2
Nadya Dimitrova et al.
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TERRA RNA Binding to TRF2 Facilitates Heterochromatin Formation and ORC Recruitment at Telomeres
Zhong Deng et al.
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Yukinori Hirano et al.
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Diego Bonetti et al.
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Multiple roles for MRE11 at uncapped telomeres
Yibin Deng et al.
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Stephane Marcand et al.
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Michelle Sabourin et al.
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The role of nonhomologous end-joining components in telomere metabolism in Kluyveromyces lactis
Sidney D. Carter et al.
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A telomeric repeat sequence adjacent to a DNA double-stranded break produces an anticheckpoint
RJ Michelson et al.
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ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1
ZS You et al.
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Isolation and characterization of novel xrs2 mutations in Saccharomyces cerevisiae
H Shima et al.
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Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage
J Falck et al.
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Effect of amino acid substitutions in the Rad50 ATP binding domain on DNA double strand break repair in yeast
L Chen et al.
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ATM-related Tel1 associates with double-strand breaks through an Xrs2-dependent mechanism
D Nakada et al.
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Sudden telomere lengthening triggers a Rad53-dependent checkpoint in Saccharomyces cerevisiae
V Viscardi et al.
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Cancer predisposition and hematopoietic failure in Rad50S/S mice
CF Bender et al.
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DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50•Mre11 complex
KM Trujillo et al.
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Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres
XD Zhu et al.
NATURE GENETICS (2000)
Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily
KP Hopfner et al.
CELL (2000)
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