4.3 Review

Losing DNA methylation at repetitive elements and breaking bad

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Decitabine Induces Gene Derepression on Monosomic Chromosomes: In Vitro and In Vivo Effects in Adverse-Risk Cytogenetics AML

Gabriele Greve et al.

Summary: This study investigated the therapeutic effects of hypomethylating agents on patients with acute myeloid leukemia/myelodysplastic syndrome, revealing that these agents can derepress genes in AML with chromosomal deletions and reactivate endogenous retroviruses, leading to improved survival rates for patients.

CANCER RESEARCH (2021)

Article Biotechnology & Applied Microbiology

Aneuploid IMR90 cells induced by depletion of pRB, DNMT1 and MAD2 show a common gene expression signature

Danilo Cilluffo et al.

GENOMICS (2020)

Article Multidisciplinary Sciences

DNA methylation patterns of LINE-1 and Alu for pre-symptomatic dementia in type 2 diabetes

Chanachai Sae-Lee et al.

PLOS ONE (2020)

Review Genetics & Heredity

Transposable Elements: A Common Feature of Neurodevelopmental and Neurodegenerative Disorders

Marie E. Jonsson et al.

TRENDS IN GENETICS (2020)

Article Medicine, Research & Experimental

Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors

Paul Dembny et al.

JCI INSIGHT (2020)

Article Biochemistry & Molecular Biology

Proliferation of aneuploid cells induced by CENP-E depletion is counteracted by the p14ARF tumor suppressor

Lorena Veneziano et al.

MOLECULAR GENETICS AND GENOMICS (2019)

Review Pharmacology & Pharmacy

Genetic variants in major depressive disorder: From pathophysiology to therapy

Xenia Gonda et al.

PHARMACOLOGY & THERAPEUTICS (2019)

Review Genetics & Heredity

DNA Methylation Reprogramming during Mammalian Development

Yang Zeng et al.

Article Multidisciplinary Sciences

Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors

Marie E. Jonsson et al.

NATURE COMMUNICATIONS (2019)

Review Neurosciences

Genetic Causes and Modifiers of Autism Spectrum Disorder

Lauren Rylaarsdam et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2019)

Review Clinical Neurology

Transposable Elements, Inflammation, and Neurological Disease

Aurian Saleh et al.

FRONTIERS IN NEUROLOGY (2019)

Review Medicine, General & Internal

Schizophrenia

Stephen R. Marder et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Genetics & Heredity

Early-life DNA methylation profiles are indicative of age-related transcriptome changes

Niran Hadad et al.

EPIGENETICS & CHROMATIN (2019)

Review Cardiac & Cardiovascular Systems

DNA methylation processes in atheosclerotic plaque

Einari Aavik et al.

ATHEROSCLEROSIS (2019)

Review Psychiatry

Epigenetic Modifications in Stress Response Genes Associated With Childhood Trauma

Shui Jiang et al.

FRONTIERS IN PSYCHIATRY (2019)

Article Neurosciences

Early life exposures, neurodevelopmental disorders, and transposable elements

Hannah E. Lapp et al.

NEUROBIOLOGY OF STRESS (2019)

Article Endocrinology & Metabolism

Increased Global DNA Hypomethylation in Distant Metastatic and Dedifferentiated Thyroid Cancer

Esther N. Klein Hesselink et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2018)

Article Neurosciences

Overexpression of LINE-1 Retrotransposons in Autism Brain

Svitlana Shpyleva et al.

MOLECULAR NEUROBIOLOGY (2018)

Review Genetics & Heredity

The DNA methyltransferase family: a versatile toolkit for epigenetic regulation

Frank Lyko

NATURE REVIEWS GENETICS (2018)

Review Clinical Neurology

Epigenetic mechanisms of major depression: Targeting neuronal plasticity

Shusaku Uchida et al.

PSYCHIATRY AND CLINICAL NEUROSCIENCES (2018)

Review Biochemistry & Molecular Biology

Transposable elements: genome innovation, chromosome diversity, and centromere conflict

Savannah J. Klein et al.

CHROMOSOME RESEARCH (2018)

Review Endocrinology & Metabolism

Early-Life Stress: From Neuroendocrine Mechanisms to Stress-Related Disorders

Panagiota Pervanidou et al.

HORMONE RESEARCH IN PAEDIATRICS (2018)

Article Biochemistry & Molecular Biology

A novel long non-coding RNA from NBL2 pericentromeric macrosatellite forms a perinucleolar aggregate structure in colon cancer

Gabrijela Dumbovic et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Genetics & Heredity

Alu siRNA to increase Alu element methylation and prevent DNA damage

Maturada Patchsung et al.

EPIGENOMICS (2018)

Article Cell Biology

Tau Activates Transposable Elements in Alzheimer's Disease

Caiwei Guo et al.

CELL REPORTS (2018)

Review Neurosciences

RNA Editing and Retrotransposons in Neurology

Heinz Krestel et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2018)

Review Cell Biology

Heterochromatin: Guardian of the Genome

Aniek Janssen et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 34 (2018)

Article Multidisciplinary Sciences

SAMHD1 acts at stalled replication forks to prevent interferon induction

Flavie Coquel et al.

NATURE (2018)

Article Psychiatry

Hypomethylation of LINE-1 elements in schizophrenia and bipolar disorder

Shufen Li et al.

JOURNAL OF PSYCHIATRIC RESEARCH (2018)

Review Biotechnology & Applied Microbiology

Ten things you should know about transposable elements

Guillaume Bourque et al.

GENOME BIOLOGY (2018)

Review Developmental Biology

LINE-1 retrotransposons in healthy and diseased human brain

Nicole A. Suarez et al.

DEVELOPMENTAL NEUROBIOLOGY (2018)

Review Medicine, General & Internal

Posttraumatic stress disorder: from diagnosis to prevention

Xue-Rong Miao et al.

MILITARY MEDICAL RESEARCH (2018)

Review Biochemistry & Molecular Biology

DNA demethylation pathways: Additional players and regulators

Matthias Bochtler et al.

BIOESSAYS (2017)

Article Biochemistry & Molecular Biology

DNMT1 mutations found in HSANIE patients affect interaction with UHRF1 and neuronal differentiation

Martha Smets et al.

HUMAN MOLECULAR GENETICS (2017)

Article Biochemistry & Molecular Biology

Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy

Kareen Bartsch et al.

HUMAN MOLECULAR GENETICS (2017)

Review Biology

Genetic conflicts: the usual suspects and beyond

Richard N. McLaughlin et al.

JOURNAL OF EXPERIMENTAL BIOLOGY (2017)

Article Neurosciences

Analysis of LINE-1 Elements in DNA from Postmortem Brains of Individuals with Schizophrenia

Glenn A. Doyle et al.

NEUROPSYCHOPHARMACOLOGY (2017)

Article Biotechnology & Applied Microbiology

Noncoding Centromeric RNA Expression Impairs Chromosome Stability in Human and Murine Stem Cells

David Y. L. Chan et al.

DISEASE MARKERS (2017)

Article Cell Biology

p14ARF Prevents Proliferation of Aneuploid Cells by Inducing p53-Dependent Apoptosis

Lorena Veneziano et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2016)

Article Biochemistry & Molecular Biology

The 3D folding of metazoan genomes correlates with the association of similar repetitive elements

Axel Cournac et al.

NUCLEIC ACIDS RESEARCH (2016)

Article Genetics & Heredity

Mutations in DNMT3B Modify Epigenetic Repression of the D4Z4 Repeat and the Penetrance of Facioscapulohumeral Dystrophy

Marlinde L. van den Boogaard et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2016)

Article Neurosciences

Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation

Rachel Yehuda et al.

BIOLOGICAL PSYCHIATRY (2016)

Article Biochemistry & Molecular Biology

Editing DNA Methylation in the Mammalian Genome

X. Shawn Liu et al.

Article Medicine, General & Internal

Systemic lupus erythematosus

Arvind Kaul et al.

NATURE REVIEWS DISEASE PRIMERS (2016)

Article Biochemistry & Molecular Biology

Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

Katherine B. Chiappinelli et al.

Article Neurosciences

Cell Lineage Analysis in Human Brain Using Endogenous Retroelements

Gilad D. Evrony et al.

NEURON (2015)

Article Multidisciplinary Sciences

Mutations in CDCA7 and HELLS cause immunodeficiency-centromeric instability-facial anomalies syndrome

Peter E. Thijssen et al.

NATURE COMMUNICATIONS (2015)

Article Geriatrics & Gerontology

Global Long Interspersed Nuclear Element 1 DNA Methylation in a Colombian Sample of Patients With Late-Onset Alzheimer's Disease

Hernan G. Hernandez et al.

AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS (2014)

Article Cell Biology

Repetitive elements dynamics in cell identity programming, maintenance and disease

Beatrice Bodega et al.

CURRENT OPINION IN CELL BIOLOGY (2014)

Article Neurosciences

Tau promotes neurodegeneration through global chromatin relaxation

Bess Frost et al.

NATURE NEUROSCIENCE (2014)

Review Neurosciences

Mobile DNA elements in the generation of diversity and complexity in the brain

Jennifer A. Erwin et al.

NATURE REVIEWS NEUROSCIENCE (2014)

Article Multidisciplinary Sciences

RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells

Rajika Arora et al.

NATURE COMMUNICATIONS (2014)

Article Cardiac & Cardiovascular Systems

Long Interspersed Nucleotide Element 1 Hypomethylation Is Associated With Poor Prognosis of Lung Adenocarcinoma

Koei Ikeda et al.

ANNALS OF THORACIC SURGERY (2013)

Article Biochemistry & Molecular Biology

Epigenomic Analysis of Multilineage Differentiation of Human Embryonic Stem Cells

Wei Xie et al.

Review Clinical Neurology

The Role of Early Life Stress in Adult Psychiatric Disorders A Systematic Review According to Childhood Trauma Subtypes

Clara Passmann Carr et al.

JOURNAL OF NERVOUS AND MENTAL DISEASE (2013)

Article Endocrinology & Metabolism

Metabolic syndrome components are associated with DNA hypomethylation

Roosmarijn Luttmer et al.

OBESITY RESEARCH & CLINICAL PRACTICE (2013)

Review Genetics & Heredity

Role of epigenetics in Rett syndrome

Takeo Kubota et al.

EPIGENOMICS (2013)

Article Rheumatology

Genetics and Epigenetics of Systemic Lupus Erythematosus

Patricia Costa-Reis et al.

CURRENT RHEUMATOLOGY REPORTS (2013)

Article Psychiatry

Epigenetic Risk Factors in PTSD and Depression

Florian Joachim Raabe et al.

Frontiers in Psychiatry (2013)

Review Biochemistry & Molecular Biology

Multiple cellular mechanisms prevent chromosomal rearrangements involving repetitive DNA

Carolyn M. George et al.

CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2012)

Article Biochemistry & Molecular Biology

Whole-genome bisulfite DNA sequencing of a DNMT3B mutant patient

Holger Heyn et al.

EPIGENETICS (2012)

Article Biochemistry & Molecular Biology

DNA replication is altered in Immunodeficiency Centromeric instability Facial anomalies (ICF) cells carrying DNMT3B mutations

Erica Lana et al.

EUROPEAN JOURNAL OF HUMAN GENETICS (2012)

Review Genetics & Heredity

Facioscapulohumeral muscular dystrophy (FSHD): an enigma unravelled?

Mark Richards et al.

HUMAN GENETICS (2012)

Article Chemistry, Multidisciplinary

Effects of DNA Methylation on the Structure of Nucleosomes

Ju Yeon Lee et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)

Article Genetics & Heredity

Mutations in Z8T824 Are Associated with Immunodeficiency, Centromeric Instability, and Facial Anomalies Syndrome Type 2

Jessica C. de Greef et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2011)

Article Immunology

DNA methylation in repetitive elements and Alzheimer disease

V. Bollati et al.

BRAIN BEHAVIOR AND IMMUNITY (2011)

Article Biochemistry & Molecular Biology

Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus

Matlock A. Jeffries et al.

EPIGENETICS (2011)

Article Genetics & Heredity

Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss

Christopher J. Klein et al.

NATURE GENETICS (2011)

Article Biochemistry & Molecular Biology

Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition

Oliver G. McDonald et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)

Article Multidisciplinary Sciences

Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells

Nicole G. Coufal et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Genetics & Heredity

Repetitive Elements May Comprise Over Two-Thirds of the Human Genome

A. P. Jason de Koning et al.

PLOS GENETICS (2011)

Article Biochemistry & Molecular Biology

Epigenetic alteration of microRNAs in DNMT3B-mutated patients of ICF syndrome

Sole Gatto et al.

EPIGENETICS (2010)

Article Cell Biology

Distinctive patterns of age-dependent hypomethylation in interspersed repetitive sequences

Pornrutsami Jintaridth et al.

PHYSIOLOGICAL GENOMICS (2010)

Article Multidisciplinary Sciences

A Unifying Genetic Model for Facioscapulohumeral Muscular Dystrophy

Richard J. L. F. Lemmers et al.

SCIENCE (2010)

Review Genetics & Heredity

Hypomethylation of repeated DNA sequences in cancer

Jason P. Ross et al.

EPIGENOMICS (2010)

Article Biotechnology & Applied Microbiology

Isolation of cancer-specific chimeric transcripts induced by hypomethylation of the LINE-1 antisense promoter

Hazel A. Cruickshanks et al.

GENOMICS (2009)

Article Cell Biology

Decline in genomic DNA methylation through aging in a cohort of elderly subjects

Valentina Bollati et al.

MECHANISMS OF AGEING AND DEVELOPMENT (2009)

Review Cell Biology

Epigenetic regulation of heterochromatic DNA stability

Jamy C. Peng et al.

CURRENT OPINION IN GENETICS & DEVELOPMENT (2008)

Review Biotechnology & Applied Microbiology

Epigenetic mechanisms of facioscapulohumeral muscular dystrophy

Jessica C. de Greef et al.

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2008)

Article Biotechnology & Applied Microbiology

Epigenetic interplay between histone modifications and DNA methylation in gene silencing

Thomas Vaissiere et al.

MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2008)

Article Multidisciplinary Sciences

DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1

Manjusha Dixit et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Genetics & Heredity

Specific sequence variations within the 4q35 region are associated with Facioscapulohumeral muscular dystrophy

Richard J. L. F. Lemmers et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2007)

Article Multidisciplinary Sciences

Chromosome territory reorganization in a human disease with altered DNA methylation

Maria R. Matarazzo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Genetics & Heredity

Clinical and molecular phenotype of Aicardi-Goutieres syndrome

Gillian Rice et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2007)

Article Multidisciplinary Sciences

UHRF1 plays a role in maintaining DNA methylation in mammalian cells

Magnolia Bostick et al.

SCIENCE (2007)

Article Clinical Neurology

Hypomethylation is restricted to the D4Z4 repeat array in phenotypic FSHD

J. C. de Greef et al.

NEUROLOGY (2007)

Review Genetics & Heredity

Transposable elements and the epigenetic regulation of the genome

R. Keith Slotkin et al.

NATURE REVIEWS GENETICS (2007)

Article Genetics & Heredity

Human genomic deletions mediated by recombination between Alu elements

Shurjo K. Sen et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2006)

Article Endocrinology & Metabolism

Transgenerational effects of posttraumatic stress disorder in babies of mothers exposed to the world trade center attacks during pregnancy

R Yehuda et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)

Article Oncology

Approval summary: Azacitidine for treatment of myelodysplastic syndrome subtypes

E Kaminskas et al.

CLINICAL CANCER RESEARCH (2005)

Article Biotechnology & Applied Microbiology

Tandem repeat copy-number variation in protein-coding regions of human genes

CT O'Dushlaine et al.

GENOME BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Subcellular distribution of HP1 proteins is altered in ICF syndrome

JJ Luciani et al.

EUROPEAN JOURNAL OF HUMAN GENETICS (2005)

Article Gastroenterology & Hepatology

Hypomethylation of L1 retrotransposons in colorectal cancer and adjacent normal tissue

CM Suter et al.

INTERNATIONAL JOURNAL OF COLORECTAL DISEASE (2004)

Article Oncology

DNA hypomethylation and ovarian cancer biology

M Widschwendter et al.

CANCER RESEARCH (2004)

Review Oncology

DNA methylation and cancer

PM Das et al.

JOURNAL OF CLINICAL ONCOLOGY (2004)

Article Biochemistry & Molecular Biology

Lsh, an epigenetic guardian of repetitive elements

JQ Huang et al.

NUCLEIC ACIDS RESEARCH (2004)

Article Genetics & Heredity

Hypomethylation of D4Z4 in 4q-linked and non-4q-linked facioscapulohumeral muscular dystrophy

PGM van Overveld et al.

NATURE GENETICS (2003)

Review Biochemistry & Molecular Biology

DNA methylation in cancer: too much, but also too little

M Ehrlich

ONCOGENE (2002)

Article Biochemistry & Molecular Biology

Replication slippage involves DNA polymerase pausing and dissociation

E Viguera et al.

EMBO JOURNAL (2001)

Review Multidisciplinary Sciences

Initial sequencing and analysis of the human genome

ES Lander et al.

NATURE (2001)

Article Biochemistry & Molecular Biology

Whole-genome methylation scan in ICF syndrome: hypomethylation of non-satellite DNA repeats D4Z4 and NBL2

T Kondo et al.

HUMAN MOLECULAR GENETICS (2000)