期刊
JOURNAL OF FUNCTIONAL FOODS
卷 83, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.jff.2021.104567
关键词
Undaria pinnatifida; Acetylcholinesterase; HMGR; LC-HRMS; MS; Phlorotannins small peptides; Proteome
资金
- Fundacao para a Ci encia e Tecnologia (FCT/MCES, Portugal)
- BioISI [UIDB/04046/2020, UIDP/04046/2020]
- CESAM [UIDP/50017/2020 + UIDB/50017/2020]
- MARE [UIDP/04292/2020, UIDB/04292/2020]
- BioSys PhD program from FCT (Portugal) [PD65-2012 [PD/BD/142861/2018]]
- Bioisi MassSpec Facility
- [PTDC/BIA-BQM/28355/2017]
- Fundação para a Ciência e a Tecnologia [PTDC/BIA-BQM/28355/2017] Funding Source: FCT
The study found that a soup prepared from this seaweed may contain bioactive compounds, such as phlorotannins and small peptides, that could promote gastrointestinal motility and reduce cholesterol biosynthesis.
Undaria pinnatifida is a brown alga, largely used as food in oriental countries. The purpose of this work was to analyze several bioactivities that might be present in different food preparations, relating them with the compounds present in the extracts. Aqueous extracts cooked, like a soup, as well as used in a salad, by simulating U. pinnatifida digestion with pancreatin were prepared. The soup preparation had anti-acetylcholinesterase activity as well as 3-hydroxy3-methyl-glutaryl coenzyme A reductase inhibition capacity, the use of 1 mg/mL, for both enzymes, caused 50% enzyme activity inhibition. The extracts produced changes in HepG2 cell proteome, mainly in the 148 kDa proteins. U. pinnatifida in salads hardly released phlorotannins to the digestive tract. The in vitro studies suggested that a soup prepared from this seaweed could deliver bioactive compounds, phlorotannins and small peptides that may facilitate the gastro-intestinal motility and reduce the cholesterol biosynthesis.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据