期刊
FRONTIERS IN CELLULAR NEUROSCIENCE
卷 15, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fncel.2021.684742
关键词
adaptation; olfactory bulb; olfaction; olfactory receptor neurons; mitral and tufted cells
资金
- DFG [MA 7804/21]
- NIH [DC016133]
- State of Florida's Consortium for Medical Marijuana Clinical Outcomes Research
- Florida State University
- University of Mainz
It remains an open question how the olfactory system adapts to different stimulus conditions and how this adaptation affects olfactory representations and perception. Although adaptation could allow the olfactory system to adjust sensory representations to the current stimulus conditions, surprisingly little is known about how adaptation changes olfactory representations and affects perception.
Olfactory stimuli are encountered across a wide range of odor concentrations in natural environments. Defining the neural computations that support concentration invariant odor perception, odor discrimination, and odor-background segmentation across a wide range of stimulus intensities remains an open question in the field. In principle, adaptation could allow the olfactory system to adjust sensory representations to the current stimulus conditions, a well-known process in other sensory systems. However, surprisingly little is known about how adaptation changes olfactory representations and affects perception. Here we review the current understanding of how adaptation impacts processing in the first two stages of the vertebrate olfactory system, olfactory receptor neurons (ORNs), and mitral/tufted cells.
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