期刊
JOURNAL OF OPTICS
卷 23, 期 7, 页码 -出版社
IOP PUBLISHING LTD
DOI: 10.1088/2040-8986/abff94
关键词
optical microscopy; bioimaging; biosensing; nano-plasmonics; ultrafast laser spectroscopy
类别
资金
- European Union [812992]
- Marie Curie Actions (MSCA) [812992] Funding Source: Marie Curie Actions (MSCA)
This article discusses the techniques needed for deciphering the chain of life from molecules to cells at the level of biomolecules, emphasizing the importance of light-matter interactions with biomolecules. These techniques and phenomena will have an impact on a wide cross-disciplinary audience.
In the quest to decipher the chain of life from molecules to cells, the biological and biophysical questions being asked increasingly demand techniques that are capable of identifying specific biomolecules in their native environment, and can measure biomolecular interactions quantitatively, at the smallest possible scale in space and time, without perturbing the system under observation. The interaction of light with biomolecules offers a wealth of phenomena and tools that can be exploited to drive this progress. This Roadmap is written collectively by prominent researchers and encompasses selected aspects of bio-nano-photonics, spanning from the development of optical micro/nano-spectroscopy technologies for quantitative bioimaging and biosensing to the fundamental understanding of light-matter interaction phenomena with biomolecules at the nanoscale. It will be of interest to a wide cross-disciplinary audience in the physical sciences and life sciences.
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