High-Precise Measurement of Optical Rotatory Dispersion Based on Weak Value Amplification

Chiroptical signals (generally very weak) play significant roles in chiral discrimination that bring great benefits in biochemistry, pharmacy, chemical, and so on. But, high-precise chiroptical detection is still a challenge. In this paper, a high-precise measurement of optical rotatory dispersion (ORD) based on weak value amplification (WVA) is presented. We proposed ORD detection method with parameter separation: by introducing complex coupling strength and dimensionless parameter intensitiy contrast ratio pointer, the ORD is only associated with the imaginary part of the weak value while circular dichroism (CD) is only associated with the real part. By designing a suitable WVA scheme, the ORD and CD can be measured separately. In the experiment, the reliability of the parameter separation method for ORD measurement is verified, and the precision reach the order of 10(-6) rad. This method has a broad application prospect in biomedical sensing, medicine, chemical analysis and other fields.

Automated summary

This paper presents a high-precise measurement of optical rotatory dispersion (ORD) based on weak value amplification (WVA). By introducing parameter separation, ORD and circular dichroism (CD) can be measured separately, verifying the reliability and precision of the method with potential applications in various fields.