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Letter
Virology
Carolina M. Voloch et al.
JOURNAL OF VIROLOGY
(2021)
Article
Multidisciplinary Sciences
Houriiyah Tegally et al.
Summary: The article describes a newly emerged lineage of SARS-CoV-2, 501Y.V2, characterized by eight mutations in the spike protein, which may result in increased transmissibility or immune escape. This lineage originated in South Africa and quickly became dominant in Eastern Cape, Western Cape, and KwaZuluNatal provinces within weeks.
Article
Multidisciplinary Sciences
Nicholas G. Davies et al.
Summary: A new variant of SARS-CoV-2 has emerged in England, with a higher reproduction number and potential for large resurgences of COVID-19 cases. Without stringent control measures, it is projected that COVID-19 hospitalizations and deaths in England for the first 6 months of 2021 will exceed those in 2020. The variant has spread globally and exhibited similar transmission increases in Denmark, Switzerland, and the United States.
Article
Multidisciplinary Sciences
Erik Volz et al.
Summary: Genetic and testing data from England indicate that the SARS-CoV-2 variant B.1.1.7 has a transmission advantage over other lineages, showing a rapid expansion during autumn 2020. Analysis of S gene target failures (SGTF) in community-based diagnostic PCR testing suggests that B.1.1.7 is more transmissible than non-variant of concern lineages and has a significant transmission advantage, with a reproduction number 50% to 100% higher. Additionally, cases of B.1.1.7 appear to include a larger share of under 20-year-olds compared to non-variant cases.
Article
Multidisciplinary Sciences
Nuno R. Faria et al.
Summary: A new variant of concern, P.1, with 17 mutations including three spike protein mutations associated with increased binding to human ACE2 receptors, emerged in Manaus, Brazil between November 2020 and January 2021. Molecular analysis suggests P.1 may be 1.7- to 2.4-fold more transmissible and that previous infection may provide 54 to 79% protection against P.1 infection compared to other lineages. Enhanced global genomic surveillance of such variants is crucial for pandemic response.
Article
Virology
Ronaldo da Silva Francisco Jr et al.
Summary: The emergence of novel SARS-CoV-2 lineages, including B.1.1.28 (E484K), in Rio Grande do Sul, Brazil has raised global concerns. Co-infection events and the identification of a new sample cluster named VUI-NP13L underscore the importance of strict and effective social distancing measures to combat the spread of potentially more hazardous SARS-CoV-2 strains.
Article
Virology
Paola Cristina Resende et al.
Summary: This study reports the identification of a new SARS-CoV-2 VOI within lineage B.1.1.33 in Brazil, which carries the S:E484K mutation. This VOI, designated as lineage N.9, emerged in August 2020 and has spread across different regions in Brazil.
Letter
Immunology
Ingra Morales Claro et al.
Summary: In December 2020, the B.1.1.7 lineage of SARS-CoV-2 was detected in Sao Paulo, Brazil, with two distinct introductions identified through rapid genomic sequencing. There may be more infections with this lineage in Brazil than officially reported.
EMERGING INFECTIOUS DISEASES
(2021)
Article
Biochemistry & Molecular Biology
Bui Quang Minh et al.
MOLECULAR BIOLOGY AND EVOLUTION
(2020)
Article
Multidisciplinary Sciences
Darlan S. Candido et al.
Article
Virology
Pavel Sagulenko et al.
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Biochemical Research Methods
Subha Kalyaanamoorthy et al.