Gut microbiota in obesity

Obesity is a major global health problem determined by heredity and environment, and its incidence is increasing yearly. In recent years, increasing evidence linking obesity to the gut microbiota has been reported. Gut microbiota management has become a new method of obesity treatment. However, the complex interactions among genetics, environment, the gut microbiota, and obesity remain poorly understood. In this review, we summarize the characteristics of the gut microbiota in obesity, the mechanism of obesity induced by the gut microbiota, and the influence of genetic and environmental factors on the gut microbiota and obesity to provide support for understanding the complex relationship between obesity and microbiota. At the same time, the prospect of obesity research related to the gut microbiota is proposed.

Automated summary

Obesity is a major global health issue affected by genetics and environment, with increasing evidence linking it to gut microbiota. Gut microbiota management has emerged as a new approach for obesity treatment, but the complex interactions among genetics, environment, microbiota, and obesity are still not well-understood. The review summarizes the characteristics of gut microbiota in obesity, the mechanisms linking gut microbiota to obesity, and the impact of genetic and environmental factors, providing insight into the complex relationship between obesity and microbiota, as well as proposing the future of gut microbiota-related obesity research.