期刊
VETERINARY RADIOLOGY & ULTRASOUND
卷 62, 期 5, 页码 610-620出版社
WILEY
DOI: 10.1111/vru.13001
关键词
functional imaging; molecular imaging; staging; tendon
Lesions of the deep digital flexor tendon in horses can be detected using F-18-FDG PET, which is more closely aligned with arterial contrast CT and T2-weighted/STIR MRI in identifying active lesions. PET provides valuable information regarding metabolic activity and can be a useful tool for diagnosing DDFT lesions in horses.
Lesions of the deep digital flexor tendon (DDFT) are a cause for foot lameness in horses. Positron emission tomography (PET) could provide valuable information regarding the metabolic activity of these lesions. The aims of this exploratory, prospective, methods comparison study were to assess the ability of (18)fluorine-fluorodeoxyglucose (F-18-FDG) PET to detect DDFT lesions and to compare the PET findings with CT and MRI findings. Eight horses with lameness due to pain localized to the front feet were included. Both front limbs of all horses were imaged with F-18-FDG PET, noncontrast CT, and arterial contrast-enhanced CT; 11 limbs were also assessed using MRI. Two observers graded independently F-18-FDG PET, noncontrast CT, arterial contrast CT, T1-weighted (T1-w) MRI, and T2-weighted (T2-w)/STIR MRI. Maximal standardized uptake values were measured. Lesions were found in seven of 16 DDFT on PET, 12 of 16 DDFT on noncontrast CT, six of 15 DDFT on arterial contrast CT, eight of 11 DDFT on T1-w MRI, and six of 11 DDFT on T2-w/STIR MRI. Positron emission tomography was in better agreement with arterial contrast CT (Kappa-weighted 0.40) and T2-w/STIR MRI (0.35) than with noncontrast CT (0.28) and T1-w MRI (0.20). Maximal standardized uptake values of lesions ranged from 1.9 to 4.6 with a median of 3.1. Chronic lesions with scar tissues identified on noncontrast CT or T1-w MRI did not have increased F-18-FDG uptake. These results demonstrated that F-18-FDG PET agreed more closely with modalities previously used to detect active tendon lesions, i.e. arterial contrast CT and T2-w/STIR MRI. (18)Fluorine-fluorodeoxyglucose PET can be used to identify metabolically active DDFT lesions in horses.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据