期刊
ULTRASOUND IN MEDICINE AND BIOLOGY
卷 47, 期 8, 页码 2117-2127出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.ultrasmedbio.2021.04.008
关键词
Diagnostic ultrasound; Shear wave elastography; Lymph nodes; Lymphomas; Performance analysis
资金
- French program Investissement d'Avenir by the Agence Nationale pour la Recherche [ANR-11-INBS-0006]
The study evaluated the diagnostic contribution of 2-D shear-wave elastography in managing superficial lymph nodes and found that SWE improved the sensitivity of LN diagnosis while decreasing its specificity, influenced by the location and histology type of the lymph nodes.
The diagnostic contribution of 2-D shear-wave elastography (SWE) in management of superficial lymph nodes (LNs) of any origin was evaluated in 222 patients referred for needle core biopsy. Each patient underwent conventional B-mode/Doppler ultrasound examinations (conventional ultrasound) and SWE. Quantitative SWE parameters and qualitative SWE map features were extracted. Carcinomas were found to be significantly stiffer than benign LNs (29.5 +/- 32.3 kPa vs. 6.7 +/- 12.3 kPa). Lymphomas exhibited intermediate stiffness (11.4 +/- 5.2 kPa). Qualitative SWE analysis provided color patterns specific to histopathology (stiff rim, nodular and undetermined patterns related to malignancy and blue pattern to benignity). Adding SWE to conventional ultrasound improved the sensitivity of LN diagnosis (from 81.1% to 92.0%) but decreased its specificity (from 73.2% to 67.6%) because of the high prevalence of lymphomas compared with carcinomas. Inter-observer agreement for quantitative SWE was good (intra-class correlation coefficient = 0.82) as was inter-observer diagnostic agreement for qualitative SWE (kappa = 0.65). LN location and histology type were found to influence the reported diagnostic performance of SWE. (C) 2021 World Federation for Ultrasound in Medicine & Biology. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据