Chromosome Instability through the Ages: Parallels between Speciation and Somatic (Cancer) Evolution

Cancer research has recently benefitted from the integration of evolutionary theory to study somatic genome evolution during tumor development. Here, we explore how investigating mechanistic principles of chromosomal instability during both species and somatic evolution can reciprocally inform each field.

Automated summary

Recent cancer research has integrated evolutionary theory to study somatic genome evolution during tumor development. Investigating mechanistic principles of chromosomal instability can reciprocally inform both species and somatic evolution fields.