相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Mechanisms of Sensitivity and Resistance to CDK4/6 Inhibition
Monica Alvarez-Fernandez et al.
CANCER CELL (2020)
Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells
Wojciech Michowski et al.
MOLECULAR CELL (2020)
A novel landscape of nuclear human CDK2 substrates revealed by in situ phosphorylation
Yong Chi et al.
SCIENCE ADVANCES (2020)
Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition
Anne Fassl et al.
SCIENCE ADVANCES (2020)
The requirement for cyclin E in c-Myc overexpressing breast cancers
Yu Zhou et al.
CELL CYCLE (2020)
Cyclin E1 Expression and Palbociclib Efficacy in Previously Treated Hormone Receptor-Positive Metastatic Breast Cancer
Nicholas C. Turner et al.
JOURNAL OF CLINICAL ONCOLOGY (2019)
CDK2 regulates the NRF1/Ehmt1 axis during meiotic prophase I
Nathan Palmer et al.
JOURNAL OF CELL BIOLOGY (2019)
The cell cycle in stem cell proliferation, pluripotency and differentiation
Lijun Liu et al.
NATURE CELL BIOLOGY (2019)
CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer
Lei Nie et al.
NATURE COMMUNICATIONS (2019)
Ubiquitin-dependent degradation of CDK2 drives the therapeutic differentiation of AML by targeting PRDX2
Meidan Ying et al.
BLOOD (2018)
Cyclin-dependent kinase 1 (CDK1) and CDK2 have opposing roles in regulating interactions of splicing factor 3B1 with chromatin
Tushar Murthy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Loss of Cyclin E1 attenuates hepatitis and hepatocarcinogenesis in a mouse model of chronic liver injury
Haksier Ehedego et al.
ONCOGENE (2018)
Kinase-independent function of E-type cyclins in liver cancer
Yan Geng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Low-Molecular-Weight Cyclin E in Human Cancer: Cellular Consequences and Opportunities for Targeted Therapies
Joseph A. Caruso et al.
CANCER RESEARCH (2018)
Cyclin E1 and cyclin-dependent kinase 2 are critical for initiation, but not for progression of hepatocellular carcinoma
Roland Sonntag et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Targeting CCl4-Induced Liver Fibrosis by RNA Interference-Mediated Inhibition of Cyclin E1 in Mice
Joerg-Martin Bangen et al.
HEPATOLOGY (2017)
G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells
Lijun Liu et al.
NATURE CELL BIOLOGY (2017)
Cytoplasmic Cyclin E Mediates Resistance to Aromatase Inhibitors in Breast Cancer
Iman Doostan et al.
CLINICAL CANCER RESEARCH (2017)
FBW7 Loss Promotes Chromosomal Instability and Tumorigenesis via Cyclin E1/CDK2-Mediated Phosphorylation of CENP-A
Mamoru Takada et al.
CANCER RESEARCH (2017)
PKCiota promotes ovarian tumor progression through deregulation of cyclin E
A. Nanos-Webb et al.
ONCOGENE (2016)
Cyclin E Associates with the Lipogenic Enzyme ATP-Citrate Lyase to Enable Malignant Growth of Breast Cancer Cells
Kimberly S. Lucenay et al.
CANCER RESEARCH (2016)
Early Adaptation and Acquired Resistance to CDK4/6 Inhibition in Estrogen Receptor-Positive Breast Cancer
Maria Teresa Herrera-Abreu et al.
CANCER RESEARCH (2016)
Irreversible APCCdh1 Inactivation Underlies the Point of No Return for Cell-Cycle Entry
Steven D. Cappell et al.
CELL (2016)
Concise Review: Control of Cell Fate Through Cell Cycle and Pluripotency Networks
Ben Boward et al.
STEM CELLS (2016)
Proteomic Landscape of Tissue-Specific Cyclin E Functions in Vivo
Junko Odajima et al.
PLOS GENETICS (2016)
CDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110
Shanhu Hu et al.
CANCER RESEARCH (2015)
Cyclin E Deregulation Promotes Loss of Specific Genomic Regions
Leonardo K. Teixeira et al.
CURRENT BIOLOGY (2015)
Whole-genome characterization of chemoresistant ovarian cancer
Ann-Marie Patch et al.
NATURE (2015)
The genetics of human infertility by functional interrogation of SNPs in mice
Priti Singh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination
Mario R. Capecchi et al.
NATURE COMMUNICATIONS (2015)
Cyclin E/Cdk2-dependent phosphorylation of Mcl-1 determines its stability and cellular sensitivity to BH3 mimetics
Gaurav S. Choudhary et al.
ONCOTARGET (2015)
Cyclin E1 Deregulation Occurs Early in Secretory Cell Transformation to Promote Formation of Fallopian Tube-Derived High-Grade Serous Ovarian Cancers
Alison M. Karst et al.
CANCER RESEARCH (2014)
DNA Replication and Oncogene-Induced Replicative Stress
Stephanie A. Hills et al.
CURRENT BIOLOGY (2014)
Concurrent Deletion of Cyclin E1 and Cyclin-Dependent Kinase 2 in Hepatocytes Inhibits DNA Replication and Liver Regeneration in Mice
Wei Hu et al.
HEPATOLOGY (2014)
Cyclin E1 Regulates Kv2.1 Channel Phosphorylation and Localization in Neuronal Ischemia
Niyathi H. Shah et al.
JOURNAL OF NEUROSCIENCE (2014)
Mammalian E-type Cyclins Control Chromosome Pairing, Telomere Stability and CDK2 Localization in Male Meiosis
Laetitia Martinerie et al.
PLOS GENETICS (2014)
A non-redundant function of cyclin E1 in hematopoietic stem cells
Stefano Campaner et al.
CELL CYCLE (2013)
Resistance to CDK2 Inhibitors Is Associated with Selection of Polyploid Cells in CCNE1-Amplified Ovarian Cancer
Dariush Etemadmoghadam et al.
CLINICAL CANCER RESEARCH (2013)
Cyclin E controls Drosophila female germline stem cell maintenance independently of its role in proliferation by modulating responsiveness to niche signals
Elizabeth T. Ables et al.
DEVELOPMENT (2013)
Foxp3 Protein Stability Is Regulated by Cyclin-dependent Kinase 2
Peter A. Morawski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Lysine Acetyltransferase GCN5 Potentiates the Growth of Non-small Cell Lung Cancer via Promotion of E2F1, Cyclin D1, and Cyclin E1 Expression
Long Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Increased replication initiation and conflicts with transcription underlie Cyclin E-induced replication stress
R. M. Jones et al.
ONCOGENE (2013)
Synthetic lethality between CCNE1 amplification and loss of BRCA1
Dariush Etemadmoghadam et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
An integrated view of cyclin E function and regulation
Ka Tat Siu et al.
CELL CYCLE (2012)
Cyclin E1 controls proliferation of hepatic stellate cells and is essential for liver fibrogenesis in mice
Yulia A. Nevzorova et al.
HEPATOLOGY (2012)
Cyclin-Dependent Kinase 2 Controls Peripheral Immune Tolerance
Neelanjana Chunder et al.
JOURNAL OF IMMUNOLOGY (2012)
Cyclin E2 Overexpression Is Associated with Endocrine Resistance but not Insensitivity to CDK2 Inhibition in Human Breast Cancer Cells
C. Elizabeth Caldon et al.
MOLECULAR CANCER THERAPEUTICS (2012)
Chemical-genetic analysis of cyclin dependent kinase 2 function reveals an important role in cellular transformation by multiple oncogenic pathways
Dai Horiuchi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Cyclin-Dependent Kinases in Brain Development and Disease
Susan C. Su et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)
Eukaryotic Origin-Dependent DNA Replication In Vitro Reveals Sequential Action of DDK and S-CDK Kinases
Ryan C. Heller et al.
CELL (2011)
Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development
Assaf C. Bester et al.
CELL (2011)
A High Proliferation Rate Is Required for Cell Reprogramming and Maintenance of Human Embryonic Stem Cell Identity
Sergio Ruiz et al.
CURRENT BIOLOGY (2011)
Cyclin E and CDK-2 regulate proliferative cell fate and cell cycle progression in the C. elegans germline
Paul M. Fox et al.
DEVELOPMENT (2011)
Cyclin E Constrains Cdk5 Activity to Regulate Synaptic Plasticity and Memory Formation
Junko Odajima et al.
DEVELOPMENTAL CELL (2011)
Cyclin E amplification/overexpression is a mechanism of trastuzumab resistance in HER2+ breast cancer patients
Maurizio Scaltriti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Cyclin E and Cdk2 Control GLD-1, the Mitosis/Meiosis Decision, and Germline Stem Cells in Caenorhabditis elegans
Johan Jeong et al.
PLOS GENETICS (2011)
Impact of cyclin E overexpression on Smad3 activity in breast cancer cell lines
Anne Cooley et al.
CELL CYCLE (2010)
Cell cycle independent role of Cyclin E during neural cell fate specification in Drosophila is mediated by its regulation of Prospero function
Christian Berger et al.
DEVELOPMENTAL BIOLOGY (2010)
The cyclin E regulator cullin 3 prevents mouse hepatic progenitor cells from becoming tumor-initiating cells
Uta Kossatz et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Cdk2 suppresses cellular senescence induced by the c-myc oncogene
Stefano Campaner et al.
NATURE CELL BIOLOGY (2010)
Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation
Per Hydbring et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Expression and functional analysis of G1 to S regulatory components reveals an important role for CDK2 in cell cycle regulation in human embryonic stem cells
I. Neganova et al.
ONCOGENE (2009)
Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells
Jan J. Molenaar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Forced G1-phase reduction alters mode of division, neuron number, and laminar phenotype in the cerebral cortex
Louis-Jan Pilaz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Inhibitor of differentiation 4 drives brain tumor-initiating cell genesis through cyclin E and notch signaling
Hye-Min Jeon et al.
GENES & DEVELOPMENT (2008)
Cyclin E-dependent localization of MCM5 regulates centrosome duplication
Rebecca L. Ferguson et al.
JOURNAL OF CELL SCIENCE (2008)
Mesothelin-Induced Pancreatic Cancer Cell Proliferation Involves Alteration of Cyclin E via Activation of Signal Transducer and Activator of Transcription Protein 3
Uddalak Bharadwaj et al.
MOLECULAR CANCER RESEARCH (2008)
Cyclin E overexpression impairs progression through mitosis by inhibiting APCCdh1
Jamie M. Keck et al.
JOURNAL OF CELL BIOLOGY (2007)
Transgenic cyclin E triggers dysplasia and multiple pulmonary adenocarcinomas
Yan Ma et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Kinase-independent function of cyclin E
Yan Geng et al.
MOLECULAR CELL (2007)
Deregulated cyclin E promotes p53 loss of heterozygosity and tumorigenesis in the mouse mammary gland
A. P. L. Smith et al.
ONCOGENE (2006)
HuR contributes to cyclin E1 deregulation in MCF-7 breast cancer cells
Xun Guo et al.
CANCER RESEARCH (2006)
Cyclin-dependent kinase 2 functions in normal DNA repair and is a therapeutic target in BRCA1-deficient cancers
Andrew J. Deans et al.
CANCER RESEARCH (2006)
CDKs promote DNA replication origin licensing in human cells by protecting Cdc6 from APC/C-dependent proteolysis
N Mailand et al.
CELL (2005)
Cdc2-cyclin E complexes regulate the G1/S phase transition
E Aleem et al.
NATURE CELL BIOLOGY (2005)
A mouse model for cyclin E-dependent genetic instability and tumorigenesis
KR Loeb et al.
CANCER CELL (2005)
Cyclin E in normal and neoplastic cell cycles
HC Hwang et al.
ONCOGENE (2005)
The structure of cyclin E1/CDK2: implications for CDK2 activation and CDK2-independent roles
R Honda et al.
EMBO JOURNAL (2005)
Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF
JY Du et al.
CANCER CELL (2004)
Deregulation of cyclin E in human cells interferes with prereplication complex assembly
S Ekholm-Reed et al.
JOURNAL OF CELL BIOLOGY (2004)
An inhibition of cyclin-dependent kinases that lengthens, but does not arrest, neuroepithelial cell cycle induces premature neurogenesis
F Calegari et al.
JOURNAL OF CELL SCIENCE (2003)
Cdk2 knockout mice are viable
C Berthet et al.
CURRENT BIOLOGY (2003)
Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells
T Parisi et al.
EMBO JOURNAL (2003)
Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice
S Ortega et al.
NATURE GENETICS (2003)
The oncogenic activity of cyclin E is not confined to Cdk2 activation alone but relies on several other, distinct functions of the protein
C Geisen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Expression of cyclins E1 and E2 during mouse development and in neoplasia
Y Geng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Cyclin E as a coactivator of the androgen receptor
A Yamamoto et al.
JOURNAL OF CELL BIOLOGY (2000)
Synergistic induction of centrosome hyperamplification by loss of p53 and cyclin E overexpression
JG Mussman et al.
ONCOGENE (2000)