相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。NINJ1 mediates plasma membrane rupture during lytic cell death
Nobuhiko Kayagaki et al.
NATURE (2021)
Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis
Kun Wang et al.
CELL (2020)
Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity-independent pyroptosis, apoptosis, necroptosis, and inflammatory disease
R. K. Subbarao Malireddi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2020)
Zebrafish GSDMEb Cleavage-Gated Pyroptosis Drives Septic Acute Kidney Injury In Vivo
Zhuang Wang et al.
JOURNAL OF IMMUNOLOGY (2020)
Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells
Zhiwei Zhou et al.
SCIENCE (2020)
N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis
Mausita Karmakar et al.
NATURE COMMUNICATIONS (2020)
Gasdermin E suppresses tumour growth by activating anti-tumour immunity
Zhibin Zhang et al.
NATURE (2020)
PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis
Junwei Hou et al.
NATURE CELL BIOLOGY (2020)
Caspase-8-dependent gasdermin D cleavage promotes antimicrobial defense but confers susceptibility to TNF-induced lethality
Benjamin Demarco et al.
SCIENCE ADVANCES (2020)
Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture
Nathalia M. de Vasconcelos et al.
CELL DEATH AND DIFFERENTIATION (2019)
Extrinsic and intrinsic apoptosis activate pannexin-1 to drive NLRP3 inflammasome assembly
Kaiwen W. Chen et al.
EMBO JOURNAL (2019)
Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells
Junhui Yu et al.
CELL DEATH & DISEASE (2019)
Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host
Matae Ahn et al.
NATURE MICROBIOLOGY (2019)
Pejvakin-mediated pexophagy protects auditory hair cells against noise-induced damage
Jean Defourny et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation
Corey Rogers et al.
NATURE COMMUNICATIONS (2019)
Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation
Sabrina Sofia Burgener et al.
CELL REPORTS (2019)
Teleost Gasdermin E Is Cleaved by Caspase 1, 3, and 7 and Induces Pyroptosis
Shuai Jiang et al.
JOURNAL OF IMMUNOLOGY (2019)
Inner ear development in cyclostomes and evolution of the vertebrate semicircular canals
Shinnosuke Higuchi et al.
NATURE (2019)
GSDMB promotes non-canonical pyroptosis by enhancing caspase-4 activity
Qin Chen et al.
JOURNAL OF MOLECULAR CELL BIOLOGY (2019)
GSDME mediates caspase-3-dependent pyroptosis in gastric cancer
Yubin Wang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
Lorenzo Galluzzi et al.
CELL DEATH AND DIFFERENTIATION (2018)
Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis
Rui Kang et al.
CELL HOST & MICROBE (2018)
A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis
Ronald A. Panganiban et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2018)
Detection and Characterization of Homologues of Human Hepatitis Viruses and Pegiviruses in Rodents and Bats in Vietnam
Dung Van Nguyen et al.
VIRUSES-BASEL (2018)
Gasdermin D Exerts Anti-inflammatory Effects by Promoting Neutrophil Death
Hiroto Kambara et al.
CELL REPORTS (2018)
Cryo-EM structure of the gasdermin A3 membrane pore
Jianbin Ruan et al.
NATURE (2018)
ASC- and caspase-8-dependent apoptotic pathway diverges from the NLRC4 inflammasome in macrophages
Bettina L. Lee et al.
SCIENTIFIC REPORTS (2018)
Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis
Bo Zhou et al.
CELL RESEARCH (2018)
Atypical Gasdermin D and Mixed Lineage Kinase Domain-like Protein Leakage Aggravates Tetrachlorobenzoquinone-Induced Nod-like Receptor Protein 3 Inflammasome Activation
Xiaomin Xia et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2018)
Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection
Joseph Sarhan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death
Pontus Orning et al.
SCIENCE (2018)
ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation
Sebastian Ruhl et al.
SCIENCE (2018)
Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome
Jaye M. Platnich et al.
CELL REPORTS (2018)
Gasdermin E Does Not Limit Apoptotic Cell Disassembly by Promoting Early Onset of Secondary Necrosis in Jurkat T Cells and THP-1 Monocytes
Rochelle Tixeira et al.
FRONTIERS IN IMMUNOLOGY (2018)
Noncanonical inflammasome signaling elicits gasdermin D-dependent neutrophil extracellular traps
Kaiwen W. Chen et al.
SCIENCE IMMUNOLOGY (2018)
Gasdermin D plays a vital role in the generation of neutrophil extracellular traps
Gabriel Sollberger et al.
SCIENCE IMMUNOLOGY (2018)
Molecular Targeted Therapies Elicit Concurrent Apoptotic and GSDME-Dependent Pyroptotic Tumor Cell Death
Haijiao Lu et al.
CLINICAL CANCER RESEARCH (2018)
MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation
Seongmin Yoon et al.
IMMUNITY (2017)
The Characterization of GSDMB Splicing and Backsplicing Profiles Identifies Novel Isoforms and a Circular RNA That Are Dysregulated in Multiple Sclerosis
Giulia Cardamone et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Enterovirus 71 Inhibits Pyroptosis through Cleavage of Gasdermin D
Xiaobo Lei et al.
JOURNAL OF VIROLOGY (2017)
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
Yupeng Wang et al.
NATURE (2017)
Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein
Kinlin L. Chao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Structure insight of GSDMD reveals the basis of GSDMD autoinhibition in cell pyroptosis
Siyun Kuang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
A subcellular map of the human proteome
Peter J. Thul et al.
SCIENCE (2017)
Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death
Corey Rogers et al.
NATURE COMMUNICATIONS (2017)
Intrinsic repair protects cells from pore-forming toxins by microvesicle shedding
Matthew Romero et al.
CELL DEATH AND DIFFERENTIATION (2017)
Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages
Cornelius Y. Taabazuing et al.
CELL CHEMICAL BIOLOGY (2017)
ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences
Yi-Nan Gong et al.
CELL (2017)
Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis
Xin Chen et al.
CELL RESEARCH (2016)
GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
Lorenzo Sborgi et al.
EMBO JOURNAL (2016)
Association Between Gasdermin A and Gasdermin B Polymorphisms and Susceptibility to Adult and Childhood Asthma Among Jordanians
Malek Zihlif et al.
GENETIC TESTING AND MOLECULAR BIOMARKERS (2016)
Pore-forming activity and structural autoinhibition of the gasdermin family
Jingjin Ding et al.
NATURE (2016)
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
Xing Liu et al.
NATURE (2016)
GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes
Robin A. Aglietti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
GSDMB induces an asthma phenotype characterized by increased airway responsiveness and remodeling without lung inflammation
Sudipta Das et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Gasdermin C Is Upregulated by Inactivation of Transforming Growth Factor β Receptor Type II in the Presence of Mutated Apc, Promoting Colorectal Cancer Proliferation
Masashi Miguchi et al.
PLOS ONE (2016)
Loss of conserved Gsdma3 self-regulation causes autophagy and cell death
Peiliang Shi et al.
BIOCHEMICAL JOURNAL (2015)
Peroxisomes Get Loud: A Redox Antidote to Hearing Loss
Pablo Mardones et al.
CELL (2015)
Hypervulnerability to Sound Exposure through Impaired Adaptive Proliferation of Peroxisomes
Sedigheh Delmaghani et al.
CELL (2015)
Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
Wan-ting He et al.
CELL RESEARCH (2015)
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
Nobuhiko Kayagaki et al.
NATURE (2015)
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
Jianjin Shi et al.
NATURE (2015)
Gasdermin-B Promotes Invasion and Metastasis in Breast Cancer Cells
Marta Hergueta-Redondo et al.
PLOS ONE (2014)
Bats are a major natural reservoir for hepaciviruses and pegiviruses
Phenix-Lan Quan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
The DFNA5 gene, responsible for hearing loss and involved in cancer, encodes a novel apoptosis-inducing protein
Ken Op de Beeck et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2011)
Polymorphisms in GSDMA and GSDMB are Associated With Asthma Susceptibility, Atopy and BHR
Jinho Yu et al.
PEDIATRIC PULMONOLOGY (2011)
Distinctive Expression and Function of Four GSDM Family Genes (GSDMA-D) in Normal and Malignant Upper Gastrointestinal Epithelium
Norihisa Saeki et al.
GENES CHROMOSOMES & CANCER (2009)
Differential expression and localisation of gasdermin-like (GSDML), a novel member of the cancer-associated GSDMDC protein family, in neoplastic and non-neoplastic gastric, hepatic, and colon tissues
Stacy Carl-Mcgrath et al.
PATHOLOGY (2008)
InCEM cells the autosomal deafness gene dfna5 is regulated by glucocorticoids and forskolin
M. S. Webb et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2007)
GASDERMIN, suppressed frequently in gastric cancer, is a target of LMO1 in TGF-β-dependent apoptotic signalling
N. Saeki et al.
ONCOGENE (2007)
Members of a novel gene family, Gsdm, are expressed exclusively in the epithelium of the skin and gastrointestinal tract in a highly tissue-specific manner
Masaru Tamura et al.
GENOMICS (2007)
Mutations in the gene encoding pejvakin, a newly identified protein of the afferent auditory pathway, cause DFNB59 auditory neuropathy
Sedigheh Delmaghani et al.
NATURE GENETICS (2006)
Mutations in gasdermin 3 cause aberrant differentiation of the hair follicle and sebaceous gland
DP Lunny et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2005)
The dominant alopecia phenotypes Bareskin, Rex-denuded, and Reduced Coat 2 are caused by mutations in gasdermin 3
F Runkel et al.
GENOMICS (2004)
Gasdermin (Gsdm) localizing to mouse Chromosome 11 is predominantly expressed in upper gastrointestinal tract bud significantly suppressed in human gastric cancer cells
N Saeki et al.
MAMMALIAN GENOME (2000)