ATP Redux

The renaissance of interest in metabolism has focused mostly on techniques to measure massive numbers of metabolites. Yet, established metabolic theory has been abandoned. Here, I highlight one misconception: how ATP (and ADP and AMP) are currently understood. A critical point was established early on: cellular [ATP] is constant.

Automated summary

The resurgence of interest in metabolism has mainly focused on measuring a large number of metabolites, neglecting established metabolic theories. This article highlights a misconception about the current understanding of ATP (along with ADP and AMP), emphasizing the crucial point that the cellular ATP concentration remains constant.