期刊
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
卷 142, 期 -, 页码 -出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2021.116306
关键词
Bioanalysis; Carbon dot; Core-shell material; Molecularly imprinted polymer; Quantum dot
This review highlights the applications of QDs/CDs and MIP conjugation technology in the field of bioanalysis. The unique properties of QDs/CDs and the selectivity of MIPs make the QD/CD-MIP conjugates highly efficient in adsorbing specific target molecules, serving as optical signal sensors. Future research directions include further enhancing the application capabilities of QD/CD-MIP in bioanalytical procedures.
Samples with complex matrix analyzed during explanation of pathogenesis of various diseases and food or environmental monitoring request advanced analytical and instrumental devices. Among the mate-rials used for described purposes, quantum (QDs) or carbon dots (CDs) layered by molecularly imprinted polymer (MIP) shells have gained widespread attention. Unique optical and physicochemical properties of QDs/CDs together with high MIPs selectivity make the QD/CD-MIP conjugates capable of adsorbing specific target molecules e such a binding event is then transduced as the optical signal of the response by the QDs/CDs. This review includes brief introduction on principles of imprinting process, QD/CD properties and QD/CD-MIP preparation techniques. Then, recent advancement of QD/CD-MIP in bio -analysis including environmental, biological and food samples investigations are summarized and emphasized. Finally, current limits of QD/CD-MIPs are defined and prospects are outlined to intensify the capability of QD/CD-MIP in future bioanalytical procedures. (c) 2021 Elsevier B.V. All rights reserved.
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