Patulin in food: A mycotoxin concern for human health and its management strategies

The mycotoxin patulin is primarily produced as a secondary metabolite by numerous fungal species and predominantly by Aspergillus, Byssochlamys, and Penicillium species. It is generally associated with fungal infected food materials. Penicillium expansum is considered the only fungal species liable for patulin contamination in pome fruits, especially in apples and apple-based products. This toxin in food poses serious health concerns and economic threat, which has aroused the need to adopt effective detection and mitigation strategies. Understanding its origin sources and biosynthetic mechanism stands essential for efficiently designing a management strategy against this fungal contamination. This review aims to present an updated outline of the sources of patulin occurrence in different foods and their biosynthetic mechanisms. It further provides information regarding the detrimental effects of patulin on human and agriculture as well as its effective detection, management, and control strategies.

Automated summary

Patulin, primarily produced by various fungal species, poses serious health and economic threats, with Penicillium expansum being the main culprit in pome fruits. Understanding its sources and biosynthetic mechanisms is crucial for designing effective management strategies against this toxin contamination. This review provides updated information on patulin occurrence in different foods, its harmful effects on human health and agriculture, and effective detection and control strategies.