4.6 Letter

Erythrocytosis and thromboembolic events in transgender individuals receiving gender-affirming testosterone

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Erythrocytosis in a Large Cohort of Trans Men Using Testosterone: A Long-Term Follow-Up Study on Prevalence, Determinants, and Exposure Years

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Summary: This study found a high prevalence of erythrocytosis in trans men using testosterone therapy, with factors such as smoking, injection method, age, body mass index (BMI), and pulmonary conditions being associated with increased risk. Recommendations for care include advising smoking cessation, switching to transdermal administration, and weight loss for those with high BMI.

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