4.4 Article

Lewis acid mediated Michael addition of non-aromatic multiple C-C bonds to α,β-unsaturated dicarbonyl compounds

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TETRAHEDRON LETTERS
卷 80, 期 -, 页码 -

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PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2021.153272

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Michael acceptors; Michael addition; alpha,beta-unsaturated dicarbonyl compounds; Lewis acids; 1,n-Zwitterions; Donor acceptor cyclopropanes

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Michael addition is a widely used method in organic synthesis for forming C-C and C-X bonds. This mini-review focuses on the addition reactions of non-activated and non-aromatic multiple C-C bonds to alpha,beta-unsaturated dicarbonyl compounds and donor-acceptor cyclopropanes under the activation of various Lewis acids.
Michael addition is widely used in organic synthesis, being one of the key methods for the formation of C-C and C-X bonds. This mini-review is focused on the addition reactions of non-activated and non-aro-matic multiple C-C bonds to alpha,beta-unsaturated dicarbonyl compounds and donor-acceptor cyclopropanes under activation of various Lewis acids. (C) 2021 Elsevier Ltd. All rights reserved.

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