Ocular syphilis

Multiple studies around the world suggest that syphilis is re-emerging. Ocular syphilis with a wide range of presentations, most of which are subtypes of uveitis - has become an increasingly common cause of ocular inflammation over the past 20 years. Its rising incidence, diagnostic complexity, and manifestations that have only recently been characterized make ocular syphilis relevant from the public health, clinical, and scientific perspectives. We review the demographics, epidemiology, clinical features, ocular imaging findings, diagnosis, and medical management of this condition. (c) 2021 Elsevier Inc. All rights reserved.

Automated summary

Multiple studies suggest the re-emergence of syphilis worldwide. Ocular syphilis, with various presentations mostly categorized as subtypes of uveitis, has become a common cause of ocular inflammation in the past 20 years. The increasing incidence, diagnostic complexity, and recently characterized manifestations make ocular syphilis relevant from public health, clinical, and scientific perspectives.