期刊
SURFACE & COATINGS TECHNOLOGY
卷 422, 期 -, 页码 -出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.surfcoat.2021.127497
关键词
Titanium; Wear resistance; Osteogenesis; Implants; Scalelike structure
资金
- National Natural Science Foundation of China [51901154, 51601124]
- Natural Science Foundation of Shanxi Province [201801D121094, 201801D221131, 201901D211092]
- Science and Technology Major Project of Shanxi [20181102013]
- 1331 Project Engineering Research Center of Shanxi [PT201801]
- Fundamental Research Funds for the Central Universities China [FRF-TP20-049A2]
The study fabricated a scalelike micro/nano-textured structure on plasma surface tantalum (Ta) alloyed Ti6Al4V substrate, improving the microhardness and wear resistance of biomedical implants. The structure enhanced the viability and spreading ability of osteoblasts, as well as promoted osteogenic activities, highlighting its promising potential in clinical practice.
Biomedical implants with hierarchical hybrid surface morphologies have been highly pursued in dental and orthopedic fields. In this study, a scalelike micro/nano-textured structure was fabricated on plasma surface tantalum (Ta) alloyed Ti6Al4V substrate by removing the Ta deposition layer. The scalelike structure is composed of interconnected nano-step arrays within grains. The orientation of nano-steps arrays becomes more complicated, and the surface roughness increases with alloying time. The microhardness and wear resistance of this scalelike structure are improved due to the solid solution strengthening effect of Ta on Ti6Al4V substrate. Besides, in vitro assays demonstrate the viability and spreading ability of osteoblasts are well retained while the initial adhesion is greatly promoted with roughness increase. The improvements in alkaline phosphatase, collagen secretion and matrix mineralization indicate the enhanced osteogenic activities of this biomimetic structure. The excellent mechanical, biocompatibility and osteogenic activities of this scalelike structure high-light their promising potential in clinical practice.
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