A novel composite of conductive metal organic framework and molecularly imprinted poly (ionic liquid) for highly sensitive electrochemical detection of bisphenol A

A novel composite of conductive metal organic framework and molecularly imprinted poly (ionic liquid) (CMOFMIPIL) was prepared for highly sensitive detection of bisphenol A (BPA). Ni-based CMOFs with various organic ligands, i.e., 2,3,6,7,10,11-hexaiminotriphenylene, hexa-aminobenzene, and 2,3,6,7,10,11-hexahydroxytriphenylene were synthesized. The electrochemical properties of the obtained Ni-based CMOFs were investigated. The results demonstrated that Ni3(HITP)2 had the highest conductivity and largest effective surface area. CMOFMIPIL was then prepared with Ni3(HITP)2 as supporter, BPA as template, and ILs as monomer and cross-linker. Under optimal conditions, CMOF-MIPIL sensor exhibited a linear range of BPA detection from 0.005 to 5.0 ?M. The detection limit was 4.0 nM. Compared with MIPIL, Ni3(HITP)2, and CMOF-NIPIL-based sensors, the performance of this sensor for BPA detection was superior due to the excellent conductivity and the presence of specific recognition sites. In addition, CMOF-MIPIL sensor had excellent selectivity for BPA. The proposed assay was used for detection of BPA in environmental water samples, plastic bottle and fresh liquid milk samples with success.

Automated summary

A novel composite material, CMOFMIPIL, combining conductive metal organic framework and molecularly imprinted poly (ionic liquid), was successfully prepared for highly sensitive detection of bisphenol A (BPA). The sensor exhibited superior performance in BPA detection due to its excellent conductivity and specific recognition sites, with successful applications in environmental water samples, plastic bottles, and fresh liquid milk samples.