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Article
Clinical Neurology
Melissa A. Walker
Summary: Hereditary myelopathies are an important and often underestimated component of neurogenetic diseases. Advances in neuroimaging and sequencing technologies have expanded classical phenotypes and challenged previous assumptions about age of onset and survival. Atypical presentations are increasingly being recognized, leading to a better understanding of the genetic basis of myelopathy and considerations for genetic testing.
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(2021)
Article
Clinical Neurology
Stephen W. English et al.
Summary: Vascular disorders of the spinal cord, including arterial ischemia, venous congestion/ischemia, hematomyelia, and extraparenchymal hemorrhage, are uncommon but can lead to significant morbidity. Recent advances in understanding and recognition of these disorders have improved diagnosis and management, potentially enhancing patient outcomes.
SEMINARS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Alice C. Shea et al.
Summary: There are multiple diverse pathologies that can present as myelopathy. The preferred method for imaging the spinal cord depends on clinical history, the specific anatomical site of interest, and any patient-related issues that may limit certain imaging modalities. This article focuses on the key role of imaging in diagnosing myelopathy, discussing physiological considerations, different imaging techniques, and various disease entities.
SEMINARS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Michael C. C. Slama et al.
Summary: Metabolic and toxic causes of myelopathy are diverse, including dietary toxins and nutritional deficiencies. Understanding the clinical presentation and pathophysiology can aid in diagnosis, with rapid identification and treatment potentially stabilizing or improving clinical deficits. Familiarity with these disorders is essential for healthcare professionals.
SEMINARS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Pria Anand
Summary: Infectious myelopathies are a significant cause of morbidity worldwide in the context of globalization and increasing use of immunosuppressive therapy. Clinical spinal cord syndromes related to infection are varied, with a wide range of causative pathogens.
SEMINARS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Kevin T. Huang et al.
Summary: Traumatic spinal cord injury is a life-changing and challenging event that requires rapid attention and collaboration between specialized medical professionals. While many patients may still experience lifelong disabilities, the increase in clinical and translational trials offers hope for new treatments in the near future.
SEMINARS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Ligia Onofrei et al.
Summary: This article discusses the epidemiology, pathophysiology, clinical assessment, natural history, and treatment options in spondylotic myelopathies, as well as diagnostic modalities and assessment instruments that can be used for evaluation. The article also covers common disorders that mimic spondylotic myelopathies and helpful diagnostic clues in differentiating spondylotic and nonspondylotic myelopathies.
SEMINARS IN NEUROLOGY
(2021)
Review
Clinical Neurology
Lama Abdel-Wahed et al.
Summary: Myelopathy refers to a group of disorders affecting the spinal cord, with a subgroup having autoimmune and inflammatory-based pathology. Symptoms can progress rapidly or have a more gradual onset, making prompt diagnosis crucial. For some patients, disabling symptoms may persist long-term.
SEMINARS IN NEUROLOGY
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Orthopedics
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INTERNATIONAL ORTHOPAEDICS
(2019)
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Clinical Neurology
Steven C. Kirshblum et al.
JOURNAL OF SPINAL CORD MEDICINE
(2011)
Article
Clinical Neurology
John K. Houten et al.
JOURNAL OF NEUROSURGERY-SPINE
(2008)
Article
Medicine, General & Internal
JR Silver
POSTGRADUATE MEDICAL JOURNAL
(2005)
Article
Clinical Neurology
A Pestronk et al.