4.4 Review

Nonclinical pharmacology of daridorexant: a new dual orexin receptor antagonist for the treatment of insomnia

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Psychology, Biological

Sleep Moderates the Relationship Between Stress and Craving in Individuals With Opioid Use Disorder

Jenni B. Teeters et al.

Summary: This study investigated the role of sleep in individuals with OUD, finding that sleep quality may influence the relationship between craving and stress. Sleep impairment could be an important target in long-term treatment plans for patients with OUD.

EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY (2021)

Article Psychology, Clinical

The relationship between sleep and opioids in chronic pain patients

Amy Frers et al.

Summary: The study found that both current and previous opioid users differed significantly from opioid-naive individuals in terms of sleep quality, duration, disturbances, and daytime dysfunction. Among those who were abstinent from opioids, there was a significant relationship between the duration of abstinence and sleep disturbances. These results suggest that opioids have a negative impact on sleep quality, even after periods of abstention, highlighting the importance of addressing sleep problems in this population.

JOURNAL OF BEHAVIORAL MEDICINE (2021)

Article Health Care Sciences & Services

Development and Validation of the Insomnia Daytime Symptoms and Impacts Questionnaire (IDSIQ)

Stacie Hudgens et al.

Summary: The study developed and evaluated the Insomnia Daytime Symptoms and Impacts Questionnaire (IDSIQ) through qualitative interviews and interventional study, demonstrating its validity and reliability. The results support the use of IDSIQ as a valid and reliable measure for deriving endpoints in insomnia clinical research trials and real-world studies.

PATIENT-PATIENT CENTERED OUTCOMES RESEARCH (2021)

Article Clinical Neurology

Daridorexant, a New Dual Orexin Receptor Antagonist to Treat Insomnia Disorder

Yves Dauvilliers et al.

ANNALS OF NEUROLOGY (2020)

Review Neurosciences

Evolution of Orexin Neuropeptide System: Structure and Function

Shingo Soya et al.

FRONTIERS IN NEUROSCIENCE (2020)

Article Medicine, General & Internal

Sleep Quality and Sleep Disturbance Perception in Dual Disorder Patients

Gianina Luca et al.

JOURNAL OF CLINICAL MEDICINE (2020)

Article Multidisciplinary Sciences

Sleep quality among individuals with ketamine use and the mediating role of craving

Cheng-Fang Yen et al.

SCIENTIFIC REPORTS (2020)

Article Psychology, Clinical

Abnormal Sleep Spindles, Memory Consolidation, and Schizophrenia

Dara S. Manoach et al.

ANNUAL REVIEW OF CLINICAL PSYCHOLOGY, VOL 15 (2019)

Article Clinical Neurology

A rodent cage change insomnia model disrupts memory consolidation

James T. McKenna et al.

JOURNAL OF SLEEP RESEARCH (2019)

Article Pharmacology & Pharmacy

Accelerated Development of the Dual Orexin Receptor Antagonist ACT-541468: Integration of a Microtracer in a First-in-Human Study

Clemens Muehlan et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2018)

Review Pharmacology & Pharmacy

Drugs for Insomnia beyond Benzodiazepines: Pharmacology, Clinical Applications, and Discovery

Tobias Atkin et al.

PHARMACOLOGICAL REVIEWS (2018)

Review Pharmacology & Pharmacy

Daily Fluctuation of Orexin Neuron Activity and Wiring: The Challenge of Chronoconnectivity

Idris A. Azeez et al.

FRONTIERS IN PHARMACOLOGY (2018)

Review Pharmacology & Pharmacy

The French addictovigilance network clinical assessment: Z-drugs, true false twins

Morgane Rousselet et al.

EXPERT OPINION ON DRUG SAFETY (2017)

Article Pharmacology & Pharmacy

The Use of Physiology-Based Pharmacokinetic and Pharmacodynamic Modeling in the Discovery of the Dual Orexin Receptor Antagonist ACT-541468

Alexander Treiber et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2017)

Review Neurosciences

Neural Circuitry of Wakefulness and Sleep

Thomas E. Scammell et al.

NEURON (2017)

Review Neurosciences

The roles of orexins in sleep/wake regulation

Michihiro Mieda

NEUROSCIENCE RESEARCH (2017)

Review Neurosciences

Role of Sleep Disturbance in the Trajectory of Alzheimer's Disease

Dong Woo Kang et al.

CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE (2017)

Article Primary Health Care

Long-term benzodiazepine and Z-drugs use in the UK

James Davies et al.

BRITISH JOURNAL OF GENERAL PRACTICE (2017)

Article Cardiac & Cardiovascular Systems

Increased activity of the orexin system in the paraventricular nucleus contributes to salt-sensitive hypertension

Michael J. Huber et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2017)

Review Critical Care Medicine

The Pathophysiology of Insomnia

Jessica C. Levenson et al.

Article Medicine, Legal

Trends in licit and illicit drug-related deaths in Florida from 2001 to 2012

Dayong Lee et al.

FORENSIC SCIENCE INTERNATIONAL (2014)

Article Psychiatry

Sleep and Substance Use Disorders: An Update

Deirdre A. Conroy et al.

CURRENT PSYCHIATRY REPORTS (2014)

Article Neurosciences

The hypocretin/orexin antagonist almorexant promotes sleep without impairment of performance in rats

Stephen R. Morairty et al.

FRONTIERS IN NEUROSCIENCE (2014)

Article Substance Abuse

Predictive Factors for Relapse in Patients on Buprenorphine Maintenance

Michael Ferri et al.

AMERICAN JOURNAL ON ADDICTIONS (2014)

Article Multidisciplinary Sciences

Human hypocretin and melanin-concentrating hormone levels are linked to emotion and social interaction

Ashley M. Blouin et al.

NATURE COMMUNICATIONS (2013)

Review Toxicology

In the Zzz Zone: The Effects of Z-Drugs on Human Performance and Driving

Naren Gunja

JOURNAL OF MEDICAL TOXICOLOGY (2013)

Article Pharmacology & Pharmacy

Orexin Receptor Antagonism, a New Sleep-Enabling Paradigm: A Proof-of-Concept Clinical Trial

P. Hoever et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2012)

Article Psychology, Biological

Acute Effects of Zolpidem Extended-Release on Cognitive Performance and Sleep in Healthy Males After Repeated Nightly Use

Bethea A. Kleykamp et al.

EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY (2012)

Article Neurosciences

The brain orexin system and almorexant in fear-conditioned startle reactions in the rat

Michel A. Steiner et al.

PSYCHOPHARMACOLOGY (2012)

Article Geriatrics & Gerontology

Influence of Zolpidem and Sleep Inertia on Balance and Cognition During Nighttime Awakening: A Randomized Placebo-Controlled Trial

Danielle J. Frey et al.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2011)

Meeting Abstract Clinical Neurology

Effect of once-daily almorexant treatment for 6 weeks on the sleep-wake cycle of normal Wistar rats

C. Brisbare-Roch et al.

EUROPEAN NEUROPSYCHOPHARMACOLOGY (2010)

Review Clinical Neurology

The hyperarousal model of insomnia: A review of the concept and its evidence

Dieter Riemann et al.

SLEEP MEDICINE REVIEWS (2010)

Review Clinical Neurology

Insomnia and health-related quality of life

Simon D. Kyle et al.

SLEEP MEDICINE REVIEWS (2010)

Review Public, Environmental & Occupational Health

Comparative Tolerability of Newer Agents for Insomnia

Gary Zammit

DRUG SAFETY (2009)

Article Neurosciences

Hypocretin /orexin contributes to the expression of some but not all forms of stress and arousal

Teri M. Furlong et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2009)

Article Multidisciplinary Sciences

Amyloid-β Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle

Jae-Eun Kang et al.

SCIENCE (2009)

Review Clinical Neurology

Hypnosedative-Induced Complex Behaviours Incidence, Mechanisms and Management

Christian R. Dolder et al.

CNS DRUGS (2008)

Review Biotechnology & Applied Microbiology

Emerging anti-insomnia drugs: tackling sleeplessness and the quality of wake time

Keith A. Wafford et al.

NATURE REVIEWS DRUG DISCOVERY (2008)

Article Biochemistry & Molecular Biology

Promotion of sleep by targeting the orexin system in rats, dogs and humans

Catherine Brisbare-Roch et al.

NATURE MEDICINE (2007)

Review Clinical Neurology

Insomnia: Pathophysiology and implications for treatment

Thomas Roth et al.

SLEEP MEDICINE REVIEWS (2007)

Review Neurosciences

The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness

Takeshi Sakurai

NATURE REVIEWS NEUROSCIENCE (2007)

Review Cell Biology

GABAA receptor diversity and pharmacology

H. Moehler

CELL AND TISSUE RESEARCH (2006)

Article Neurosciences

Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle

MG Lee et al.

JOURNAL OF NEUROSCIENCE (2005)

Article Biochemistry & Molecular Biology

Orexins activate histaminergic neurons via the orexin 2 receptor

A Yamanaka et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)

Article Geriatrics & Gerontology

Subjective sleep problems in later life as predictors of cognitive decline. Report from the Maastricht Ageing Study (MAAS)

M Jelicic et al.

INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2002)

Article Geriatrics & Gerontology

Zolpidem use and hip fractures in older people

PS Wang et al.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2001)

Article Neurosciences

Differential expression of orexin receptors 1 and 2 in the rat brain

JN Marcus et al.

JOURNAL OF COMPARATIVE NEUROLOGY (2001)

Review Clinical Neurology

Chronic hypnotic use: deadly risks, doubtful benefit

DF Kripke

SLEEP MEDICINE REVIEWS (2000)