Unmet supportive care needs, anxiety and depression in haematology patients during watch-and-wait

Objective There is growing evidence and awareness of the psychological impact of watch-and-wait in patients with indolent haematological malignancy. However, the need for supportive care is unknown. The aims of this study were to investigate prevalence of unmet needs, their psychological associates, and prevalence of anxiety and depressive symptomatology. Methods Adult patients with indolent haematological malignancy, during watch-and-wait (n = 122) were included in this cross-sectional single-centre study. Participants filled out questionnaires on anxiety (Generalised Anxiety Disorder), depression (Patient Health Questionnaire), coping (Acceptance and Action Questionnaire II), distress (distress thermometer), disease-specific quality of life (The European Organisation for Research and Treatment of Cancer quality of life questionnaire) and supportive care needs (Supportive care needs survey - Dutch short version). Multiple linear regression analyses were performed to identify patient-factors associated with unmet needs. Results The prevalence of anxiety and depressive symptomatology were both 7.3%. Unmet needs were reported by 35% (n = 43) of patients. After controlling for covariates, higher levels of distress (beta = 0.23, p = 0.05), depression (beta = 0.41, p = 0.001), poorer coping (beta = 0.35, p = 0.002) and younger age (beta = -0.16, p = 0.05) were independently associated with more supportive care needs. The highest unmet needs were reported in domain health system, information & patient support (mean = 23.6 +/- 23.0) and psychological domain (mean = 18.7 +/- 21.8). Conclusions One third of indolent haematology patients during watch-and-wait report unmet supportive care needs. Screening for unmet needs and design of interventions is required. A joint approach focused on psychological care, especially on improving psychological flexibility, should be combined with promoting accessibility to health-services and optimising disease education.

Automated summary

The study found that one third of patients with indolent haematological malignancy during watch-and-wait reported unmet supportive care needs. The prevalence of anxiety and depressive symptomatology were both 7.3%. Factors such as higher distress levels, depression, poorer coping, and younger age were independently associated with more supportive care needs.