4.8 Article

Market forces determine the distribution of a leaky function in a simple microbial community

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Article Multidisciplinary Sciences

Market forces determine the distribution of a leaky function in a simple microbial community

Sarah J. Adkins-Jablonsky et al.

Summary: This passage discusses how leaky biological functions are distributed in microbial communities, with a focus on the distribution of antibiotic resistance genes in Escherichia coli based on the market principle of comparative advantage. Results show that antibiotic-sensitive cells can invade communities of antibiotic-resistant cells, leading to fixation of antibiotic sensitivity in one species. The intrinsic resistance level and opportunity cost of resistance, rather than absolute cost or efficiency of antibiotic removal, determine which species becomes the sole beneficiary, highlighting the role of comparative advantage in evolutionary dynamics.

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