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Feng-Guo Zhai et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2009)
Mechanisms of hypoxic pulmonary vasoconstriction and their roles in pulmonary hypertension: new findings for an old problem
Jeremy P. T. Ward et al.
CURRENT OPINION IN PHARMACOLOGY (2009)
Pulmonary arterial pressure during rest and exercise in healthy subjects: a systematic review
G. Kovacs et al.
EUROPEAN RESPIRATORY JOURNAL (2009)
Dichloroacetate treatment partially regresses established pulmonary hypertension in mice with SM22α-targeted overexpression of the serotonin transporter
Christophe Guignabert et al.
FASEB JOURNAL (2009)
17β-Estradiol Modulates Apoptosis in Pancreatic β-Cells by Specific Involvement of the Sulfonylurea Receptor (SUR) Isoform SUR1
Stefanie Ackermann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Heterogeneity in function of small artery smooth muscle BKCa: involvement of the β1-subunit
Yan Yang et al.
JOURNAL OF PHYSIOLOGY-LONDON (2009)
De novo expression of Kv6.3 contributes to changes in vascular smooth muscle cell excitability in a hypertensive mice strain
Alejandro Moreno-Dominguez et al.
JOURNAL OF PHYSIOLOGY-LONDON (2009)
Voltage-gated potassium channels as therapeutic targets
Heike Wulff et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
Endothelin-1 mediates hypoxia-induced inhibition of voltage-gated K+ channel expression in pulmonary arterial myocytes
E. Miles Whitman et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2008)
Potassium channels in the regulation of pulmonary artery smooth muscle cell proliferation and apoptosis: pharmacotherapeutic implications
E. D. Burg et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
An antiproliferative BMP-2/PPARγ/apoE axis in human and murine SMCs and its role in pulmonary hypertension
Georg Hansmann et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Release of neuroendocrine products in the pulmonary circulation during intermittent hypoxia in isolated rat lung
Sveinung Sorhaug et al.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2008)
Ion channel switching and activation in smooth-muscle cells of occlusive vascular diseases
D. J. Beech
BIOCHEMICAL SOCIETY TRANSACTIONS (2007)
Role of protein kinase Cζ and its adaptor protein p62 in voltage-gated potassium channel modulation in pulmonary arteries
Laura Moreno et al.
MOLECULAR PHARMACOLOGY (2007)
An epidemiological study of pulmonary arterial hypertension
A. J. Peacock et al.
EUROPEAN RESPIRATORY JOURNAL (2007)
Inhibition by cocaine of G protein-activated inwardly rectifying K+ channels expressed in Xenopus oocytes
Toru Kobayashi et al.
TOXICOLOGY IN VITRO (2007)
Function of Kv1.5 channels and genetic variations of KCNA5 in patients with idiopathic pulmonary arterial hypertension
Carmelle V. Remillard et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)
Mechanisms controlling vascular tone in pulmonary arterial hypertension: Implications for vasodilator therapy
Angel Cogolludo et al.
PHARMACOLOGY (2007)
The role of K+ channels in determining pulmonary vascular tone, oxygen sensing, cell proliferation, and apoptosis:: Implications in hypoxic pulmonary vasoconstriction and pulmonary arterial hypertension
Rohit Moudgil et al.
MICROCIRCULATION (2006)
Angiotensin II activates intermediate-conductance Ca2+-activated K+ channels in arterial smooth muscle cells
Yasunobu Hayabuchi et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2006)
Nitric oxide blocks hKv1.5 channels by S-nitrosylation and by a cyclic GMP-dependent mechanism
Lucia Nunez et al.
CARDIOVASCULAR RESEARCH (2006)
Kv2 channels oppose myogenic constriction of rat cerebral arteries
Gregory C. Amberg et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
An abnormal mitochondrial-hypoxia inducible factor-1α-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats -: Similarities to human pulmonary arterial hypertension
Sébastien Bonnet et al.
CIRCULATION (2006)
Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension
Christophe Guignabert et al.
CIRCULATION RESEARCH (2006)
BMP signaling controls PASMC KV channel expression in vitro and in vivo
KA Young et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2006)
Pulmonary arterial hypertension in France - Results from a national registry
M Humbert et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2006)
Impact of TASK-1 in human pulmonary artery smooth muscle cells
A Olschewski et al.
CIRCULATION RESEARCH (2006)
Cross talk between endothelial and smooth muscle cells in pulmonary hypertension - Critical role for serotonin-induced smooth muscle hyperplasia
S Eddahibi et al.
CIRCULATION (2006)
Serotonin inhibits voltage-gated K+ currents in pulmonary artery smooth muscle cells -: Role of 5-HT2A receptors, caveolin-1, and KV1.5 channel internalization
A Cogolludo et al.
CIRCULATION RESEARCH (2006)
NOX4 as an oxygen sensor to regulate TASK-1 activity
YM Lee et al.
CELLULAR SIGNALLING (2006)
KATP channels as molecular sensors of cellular metabolism
CG Nichols
NATURE (2006)
Glibenclamide-induced apoptosis is specifically enhanced by expression of the sulfonylurea receptor isoform SUR1 but not by expression of SUR2B or the mutant SUR1(M1289T)
A Hambrock et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Investigation of the role of TASK-2 channels in rat pulmonary arteries;: pharmacological and functional studies following RNA interference procedures
M Gönczi et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
Hypoxic pulmonary vasoconstriction: mechanisms and controversies
PI Aaronson et al.
JOURNAL OF PHYSIOLOGY-LONDON (2006)
Role of ion channels in acute and chronic responses of the pulmonary vasculature to hypoxia
E. Kenneth Weir et al.
CARDIOVASCULAR RESEARCH (2006)
Regulation of hypoxia-inducible factor 1 by prolyl and asparaginyl hydroxylases
K Hirota et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Down-regulation of endogenous hydrogen sulfide pathway in pulmonary hypertension and pulmonary vascular structural remodeling induced by high pulmonary blood flow in rats
XH Li et al.
CIRCULATION JOURNAL (2005)
Pergolide is an inhibitor of voltage-gated potassium channels, including Kv1.5, and causes pulmonary vasoconstriction
ZG Hong et al.
CIRCULATION (2005)
Kv1.5 surface expression is modulated by retrograde trafficking of newly endocytosed channels by the dynein motor
WS Choi et al.
CIRCULATION RESEARCH (2005)
KATP channel therapeutics at the bedside
A Jahangir et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2005)
Chronic hypoxia inhibits Kv channel gene expression in rat distal pulmonary artery
J Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2005)
KATP channel:: relation with cell metabolism and role in the cardiovascular system
ML Zhuo et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2005)
Postnatal maturational shift from PKC and voltage-gated K+ channels to RhoA/Rho kinase in pulmonary vasoconstriction
A Cogolludo et al.
CARDIOVASCULAR RESEARCH (2005)
Heteromultimeric Kv1 channels contribute to myogenic control of arterial diameter
F Plane et al.
CIRCULATION RESEARCH (2005)
Functional evidence of a role for two-pore domain potassium channels in rat mesenteric and pulmonary arteries
MJ Gardener et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
Mutual functional destruction of HIV-1 Vpu and host TASK-1 channel
K Hsu et al.
MOLECULAR CELL (2004)
Endothelial dysfunction in pulmonary hypertension
R Budhiraja et al.
CIRCULATION (2004)
Drug therapy: Treatment of pulmonary arterial hypertension
M Humbert et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Overexpression of human KCNA5 increases IK(V) and enhances apoptosis
EE Brevnova et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2004)
Hyperinsulinism in infancy: From basic science to clinical disease
MJ Dunne et al.
PHYSIOLOGICAL REVIEWS (2004)
Overexpression of the 5-hydroxytryptamine transporter gene - Effect on pulmonary hemodynamics and hypoxia-induced pulmonary hypertension
MR MacLean et al.
CIRCULATION (2004)
Molecular and functional analysis identifies ALK-1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasia
RE Harrison et al.
JOURNAL OF MEDICAL GENETICS (2003)
Two-pore domain K channel, TASK-1, in pulmonary artery smooth muscle cells
AM Gurney et al.
CIRCULATION RESEARCH (2003)
Role of Ca2+-sensitive K+ channels in the remission phase of pulmonary hypertension in chronic obstructive pulmonary diseases
S Bonnet et al.
CARDIOVASCULAR RESEARCH (2003)
Thromboxane A2-induced inhibition of voltage-gated K+ channels and pulmonary vasoconstriction -: Role of protein kinase Cζ
A Cogolludo et al.
CIRCULATION RESEARCH (2003)
Shear stress increases expression of a KATP channel in rat and bovine pulmonary vascular endothelial cells
S Chatterjee et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2003)
Bone morphogenetic proteins induce apoptosis in human pulmonary vascular smooth muscle cells
S Zhang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2003)
Role of the cytosolic chaperones Hsp70 and Hsp90 in maturation of the cardiac potassium channel hERG
E Ficker et al.
CIRCULATION RESEARCH (2003)
Pseudoacromegaly induced by the long-term use of minoxidil
KH Nguyen et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2003)
In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction chronically hypoxic rats
ZI Pozeg et al.
CIRCULATION (2003)
A-type potassium currents in smooth muscle
GC Amberg et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2003)
Pulmonary vascular K+ channel expression and vasoreactivity in a model of congenital heart disease
DN Cornfield et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2002)
Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension
JM Launay et al.
NATURE MEDICINE (2002)
Endothelial cells freshly isolated from small pulmonary arteries of the rat possess multiple distinct K+ current profiles
DS Hogg et al.
LUNG (2002)
Activation of K+ channels and increased migration of differentiated intestinal epithelial cells after wounding
JN Rao et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2002)
The molecular composition of K(ATP) channels in human pulmonary artery smooth muscle cells and their modulation by growth
Y Cui et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2002)
Identification of a trafficking determinant localized to the Kv1 potassium channel pore
LN Manganas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Inhibition of voltage-gated K+ currents by endothelin-1 in human pulmonary arterial myocytes
LA Shimoda et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2001)
Determinants involved in Kv1 potassium channel folding in the endoplasmic reticulum, glycosylation in the Golgi, and cell surface expression
J Zhu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Pulmonary artery vasoconstriction but not [Ca2+]i signal stimulated by thromboxane A2 is partially resistant to NO
F Pérez-Vizcaíno et al.
PEDIATRIC RESEARCH (2001)
Ion channels and their functional role in vascular endothelium
B Nilius et al.
PHYSIOLOGICAL REVIEWS (2001)
Partial HIF-1α deficiency impairs pulmonary arterial myocyte electrophysiological responses to hypoxia
LA Shimoda et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2001)
Molecular physiology of oxygen-sensitive potassium channels
AJ Patel et al.
EUROPEAN RESPIRATORY JOURNAL (2001)
Chronic hypoxia decreases KV channel expression and function in pulmonary artery myocytes
O Platoshyn et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2001)
Activation of K+ channels induces apoptosis in vascular smooth muscle cells
S Krick et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2001)
Mechanisms involved in SNP-induced relaxation and [Ca2+]i reduction in piglet pulmonary and systemic arteries
AL Cogolludo et al.
BRITISH JOURNAL OF PHARMACOLOGY (2001)
BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension
RD Machado et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2001)
Role of endothelin-1 in lung disease
KA Fagan et al.
RESPIRATORY RESEARCH (2001)
Mechanisms of NO/cGMP-dependent vasorelaxation
M Sausbier et al.
CIRCULATION RESEARCH (2000)
Normotonic cell shrinkage because of disordered volume regulation is an early prerequisite to apoptosis
E Maeno et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Surface expression of Kv1 channels is governed by a C-terminal motif
DQ Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
HIF-1: mediator of physiological and pathophysiological responses to hypoxia
GL Semenza
JOURNAL OF APPLIED PHYSIOLOGY (2000)
Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension
KB Lane et al.
NATURE GENETICS (2000)
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