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Development of a Series of Aryl Pyrimidine Kynurenine Monooxygenase Inhibitors as Potential Therapeutic Agents for the Treatment of Huntington's Disease
Leticia M. Toledo-Sherman et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Kynurenine causes vasodilation and hypotension induced by activation of KCNQ-encoded voltage-dependent K+ channels
Kensuke Sakakibara et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2015)
Increased Plasma Levels of Xanthurenic and Kynurenic Acids in Type 2 Diabetes
Gregory F. Oxenkrug
MOLECULAR NEUROBIOLOGY (2015)
Elevated levels of kynurenic acid during gestation produce neurochemical, morphological, and cognitive deficits in adulthood: Implications for schizophrenia
Michelle L. Pershing et al.
NEUROPHARMACOLOGY (2015)
ALTERED HIPPOCAMPAL PLASTICITY BY PRENATAL KYNURENINE ADMINISTRATION, KYNURENINE-3-MONOXYGENASE (KMO) DELETION OR GALANTAMINE
C. M. Forrest et al.
NEUROSCIENCE (2015)
The kynurenine pathway and neurodegenerative disease
Daniel C. Maddison et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2015)
The transcriptional landscape of age in human peripheral blood
Marjolein J. Peters et al.
NATURE COMMUNICATIONS (2015)
Amino acids inhibit kynurenic acid formation via suppression of kynurenine uptake or kynurenic acid synthesis in rat brain in vitro
Airi Sekine et al.
SPRINGERPLUS (2015)
Extensive Profiling of the Expression of the Indoleamine 2,3-Dioxygenase 1 Protein in Normal and Tumoral Human Tissues
Ivan Theate et al.
CANCER IMMUNOLOGY RESEARCH (2015)
Treadmill exercise improves short-term memory by enhancing hippocampal cell proliferation in quinolinic acid-induced Huntington's disease rats
You-Mi Kim et al.
JOURNAL OF EXERCISE REHABILITATION (2015)
A tryptophan metabolite, kynurenine, promotes mast cell activation through aryl hydrocarbon receptor
H. Kawasaki et al.
ALLERGY (2014)
The kynurenine pathway contributes to long-term neuropsychological changes in experimental pneumococcal meningitis
Lay Khoon Too et al.
BEHAVIOURAL BRAIN RESEARCH (2014)
Contributions of tryptophan 2,3-dioxygenase and indoleamine 2,3-dioxygenase to the conversion of D-tryptophan to nicotinamide analyzed by using tryptophan 2,3-dioxygenase-knockout mice
Akihiro Maeta et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2014)
Lavender oil suppresses indoleamine 2,3-dioxygenase activity in human PBMC
Johanna M. Gostner et al.
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2014)
Behavioral disturbances in adult mice following neonatal virus infection or kynurenine treatment - Role of brain kynurenic acid
Xi-Cong Liu et al.
BRAIN BEHAVIOR AND IMMUNITY (2014)
Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression
Leandro Z. Agudelo et al.
CELL (2014)
L-Kynurenine/Aryl Hydrocarbon Receptor Pathway Mediates Brain Damage After Experimental Stroke
Maria I. Cuartero et al.
CIRCULATION (2014)
Effects of systemic administration of kynurenic acid and glycine on renal haemodynamics and excretion in normotensive and spontaneously hypertensive rats
Bozena Badzynska et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2014)
Inhibition of stress-induced hepatic tryptophan 2,3-dioxygenase exhibits antidepressant activity in an animal model of depressive behaviour
Sinead M. Gibney et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2014)
Indoleamine 2,3-Dioxygenase 1 (IDO1) Is Up-Regulated in Thyroid Carcinoma and Drives the Development of an Immunosuppressant Tumor Microenvironment
Sonia Moretti et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2014)
IDO2 Is a Critical Mediator of Autoantibody Production and Inflammatory Pathogenesis in a Mouse Model of Autoimmune Arthritis
Lauren M. F. Merlo et al.
JOURNAL OF IMMUNOLOGY (2014)
Kynurenine Increases Matrix Metalloproteinase-1 and-3 Expression in Cultured Dermal Fibroblasts and Improves Scarring In Vivo
Yunyuan Li et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2014)
The kynurenine pathway is involved in bacterial meningitis
Leonam G. Coutinho et al.
JOURNAL OF NEUROINFLAMMATION (2014)
Reduction of Brain Kynurenic Acid Improves Cognitive Function
Rouba Kozak et al.
JOURNAL OF NEUROSCIENCE (2014)
The KMO allele encoding Arg452 is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression
C. Lavebratt et al.
MOLECULAR PSYCHIATRY (2014)
Yucasin is a potent inhibitor of YUCCA, a key enzyme in auxin biosynthesis
Takeshi Nishimura et al.
PLANT JOURNAL (2014)
Effects of Various Phytochemicals on Indoleamine 2,3-Dioxygenase 1 Activity: Galanal Is a Novel, Competitive Inhibitor of the Enzyme
Rie Yamamoto et al.
PLOS ONE (2014)
IDO1 and IDO2 Non-Synonymous Gene Variants: Correlation with Crohn's Disease Risk and Clinical Phenotype
Alexander Lee et al.
PLOS ONE (2014)
Involvement of the Kynurenine Pathway in Human Glioma Pathophysiology
Seray Adams et al.
PLOS ONE (2014)
Continuous kynurenine administration during the prenatal period, but not during adolescence, causes learning and memory deficits in adult rats
Ana Pocivavsek et al.
PSYCHOPHARMACOLOGY (2014)
Targeting Kynurenine Aminotransferase II in Psychiatric Diseases: Promising Effects of an Orally Active Enzyme Inhibitor
Hui-Qiu Wu et al.
SCHIZOPHRENIA BULLETIN (2014)
IDO is highly expressed in breast cancer and breast cancer-derived circulating microvesicles and associated to aggressive types of tumors by in silico analysis
M. T. Isla Larrain et al.
TUMOR BIOLOGY (2014)
Early Activation of the Kynurenine Pathway Predicts Early Death and Long-term Outcome in Patients Resuscitated From Out-of-Hospital Cardiac Arrest
Giuseppe Ristagno et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2014)
Tryptophan-catabolizing enzymes - party of three
Helen J. Ball et al.
FRONTIERS IN IMMUNOLOGY (2014)
Aryl hydrocarbon receptor ligands in cancer: friend and foe
Iain A. Murray et al.
NATURE REVIEWS CANCER (2014)
Characterization of Functional Polymorphisms and Glucocorticoid-Responsive Elements in the Promoter of TDO2, a Candidate Gene for Ethanol-Induced Behavioural Disorders
Marion Soichot et al.
ALCOHOL AND ALCOHOLISM (2013)
Serotonin - Kynurenine Hypothesis of Depression: Historical Overview and Recent Developments
Gregory Oxenkrug
CURRENT DRUG TARGETS (2013)
IDO1 Metabolites Activate β-catenin Signaling to Promote Cancer Cell Proliferation and Colon Tumorigenesis in Mice
Ameet I. Thaker et al.
GASTROENTEROLOGY (2013)
Systemic metabolism of tryptophan and its catabolites, kynurenine and 3-HAA, in mice with inflammatory arthritis
Lukasz Kolodziej
GENE (2013)
Indoleamine 2,3 dioxygenase gene polymorphisms correlate with CD8+Treg impairment in systemic sclerosis
Samuele Tardito et al.
HUMAN IMMUNOLOGY (2013)
Targeted Deletion of Kynurenine 3-Monooxygenase in Mice A NEW TOOL FOR STUDYING KYNURENINE PATHWAY METABOLISM IN PERIPHERY AND BRAIN
Flaviano Giorgini et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Analysis of indole compounds in methanolic extracts from the fruiting bodies of Cantharellus cibarius (the Chanterelle) and from the mycelium of this species cultured in vitro
Bozena Muszynska et al.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE (2013)
A Mathematical Model of Tryptophan Metabolism via the Kynurenine Pathway Provides Insights into the Effects of Vitamin B-6 Deficiency, Tryptophan Loading, and Induction of Tryptophan 2,3-Dioxygenase on Tryptophan Metabolites
Luisa Rios-Avila et al.
JOURNAL OF NUTRITION (2013)
Insulin Resistance and Dysregulation of Tryptophan-Kynurenine and Kynurenine-Nicotinamide Adenine Dinucleotide Metabolic Pathways
Gregory Oxenkrug
MOLECULAR NEUROBIOLOGY (2013)
The Cancer Genome Atlas Pan-Cancer analysis project
John N. Weinstein et al.
NATURE GENETICS (2013)
Kynurenines in the CNS: recent advances and new questions
Laszlo Vecsei et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
EARLY DEVELOPMENTAL ELEVATIONS OF BRAIN KYNURENIC ACID IMPAIR COGNITIVE FLEXIBILITY IN ADULTS: REVERSAL WITH GALANTAMINE
K. S. Alexander et al.
NEUROSCIENCE (2013)
3-Hydroxykynurenine: An intriguing molecule exerting dual actions in the Central Nervous System
Ana Laura Colin-Gonzalez et al.
NEUROTOXICOLOGY (2013)
The effect of transient increases in kynurenic acid and quinolinic acid levels early in life on behavior in adulthood: Implications for schizophrenia
Hannah F. Iaccarino et al.
SCHIZOPHRENIA RESEARCH (2013)
Investigation of the kynurenine pathway in Indoleamine 2, 3 dioxygenase deficient mice with inflammatory arthritis
Lukasz Kolodziej
TRANSGENIC RESEARCH (2013)
The emerging world of the fungal microbiome
Gary B. Huffnagle et al.
TRENDS IN MICROBIOLOGY (2013)
Peripheral regulatory cells immunophenotyping in Primary Sjogren's Syndrome: a cross-sectional study
Janette Furuzawa-Carballeda et al.
ARTHRITIS RESEARCH & THERAPY (2013)
IL-22 and IDO1 Affect Immunity and Tolerance to Murine and Human Vaginal Candidiasis
Antonella De Luca et al.
PLOS PATHOGENS (2013)
Tryptophan metabolism activation by indoleamine 2,3-dioxygenase in adipose tissue of obese women: an attempt to maintain immune homeostasis and vascular tone
Isabelle Wolowczuk et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2012)
Human Microbiome in Health and Disease
Kathryn J. Pflughoeft et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 7 (2012)
Clinicopathological significance of indoleamine 2,3-dioxygenase 1 expression in colorectal cancer
L. Ferdinande et al.
BRITISH JOURNAL OF CANCER (2012)
Blood pressure reducing effects of Phalaris canariensis in normotensive and spontaneously hypertensive rats
Clevia Santos Passos et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2012)
Tryptophan degradation and neopterin levels in treated rheumatoid arthritis patients
Yesim Ozkan et al.
CLINICAL RHEUMATOLOGY (2012)
Indoleamine 2,3-dioxygenase expression in human inflammatory bowel disease
Liping Zhou et al.
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2012)
Pre- and postnatal exposure to kynurenine causes cognitive deficits in adulthood
Ana Pocivavsek et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2012)
Indoleamine 2,3-dioxygenase mediates anhedonia and anxiety-like behaviors caused by peripheral lipopolysaccharide immune challenge
Alexander Salazar et al.
HORMONES AND BEHAVIOR (2012)
Studies on Tissue and Cellular Distribution of Indoleamine 2,3-Dioxygenase 2: The Absence of IDO1 Upregulates IDO2 Expression in the Epididymis
Masakazu Fukunaga et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2012)
The kynurenine system and immunoregulation
Yvette Mandi et al.
JOURNAL OF NEURAL TRANSMISSION (2012)
Common genetic variation in the indoleamine-2,3-dioxygenase genes and antidepressant treatment outcome in major depressive disorder
Jessica A. Cutler et al.
JOURNAL OF PSYCHOPHARMACOLOGY (2012)
Association of a polymorphism in the indoleamine-2,3-dioxygenase gene and interferon-α-induced depression in patients with chronic hepatitis C
A. K. Smith et al.
MOLECULAR PSYCHIATRY (2012)
Kynurenines in the mammalian brain: when physiology meets pathology
Robert Schwarcz et al.
NATURE REVIEWS NEUROSCIENCE (2012)
Potato- An Important Source of Nutritional Kynurenic Acid
Michal P. Turski et al.
PLANT FOODS FOR HUMAN NUTRITION (2012)
Interaction and transport of kynurenic acid via human organic anion transporters hOAT1 and hOAT3
Yuichi Uwai et al.
PHARMACOLOGICAL RESEARCH (2012)
Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase
Luc Pilotte et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Plasma Indoleamine 2,3-Dioxygenase Concentration is Increased in Hemodialysis Patients and May Contribute to the Pathogenesis of Coronary Heart Disease
Theodoros Eleftheriadis et al.
RENAL FAILURE (2012)
Exposure to Kynurenic Acid During Adolescence Produces Memory Deficits in Adulthood
Cynthia O. Akagbosu et al.
SCHIZOPHRENIA BULLETIN (2012)
Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors for Schizophrenia
Arny B. Dounay et al.
ACS MEDICINAL CHEMISTRY LETTERS (2012)
Effects of adalimumab therapy on disease activity and interferon-γ-mediated biochemical pathways in patients with rheumatoid arthritis
Katharina Kurz et al.
AUTOIMMUNITY (2011)
Association of kynurenine aminotransferase II gene C401T polymorphism with immune response in patients with meningitis
Fladjule Rejane Soares de Souza et al.
BMC MEDICAL GENETICS (2011)
A Rare Variant at the KYNU Gene Is Associated With Kynureninase Activity and Essential Hypertension in the Han Chinese Population
Yi Zhang et al.
CIRCULATION-CARDIOVASCULAR GENETICS (2011)
Changes in kynurenine pathway metabolism in the brain, liver and kidney of aged female Wistar rats
Nady Braidy et al.
FEBS JOURNAL (2011)
Molecular evolution of bacterial indoleamine 2,3-dioxygenase
Hajime J. Yuasa et al.
GENE (2011)
Indole Compounds in Some Culinary-Medicinal Higher Basidiomycetes from Poland
Bozena Muszynska et al.
INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS (2011)
Simultaneous determination of tryptophan, kynurenine, kynurenic and xanthurenic acids in honey by liquid chromatography with diode array, fluorescence and tandem mass spectrometry detection
Maria E. Soto et al.
JOURNAL OF CHROMATOGRAPHY A (2011)
Simultaneous determination of urinary tryptophan, tryptophan-related metabolites and creatinine by high performance liquid chromatography with ultraviolet and fluorimetric detection
Jianxing Zhao et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2011)
Coding region polymorphisms in the indoleamine 2,3-dioxygenase (INDO) gene and recurrent spontaneous abortion
Dawar Amani et al.
JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2011)
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
Christiane A. Opitz et al.
NATURE (2011)
Expression and prognostic impact of indoleamine 2,3-dioxygenase in oral squamous cell carcinomas
Klaus Laimer et al.
ORAL ONCOLOGY (2011)
A Small-Molecule Screen Identifies L-Kynurenine as a Competitive Inhibitor of TAA1/TAR Activity in Ethylene-Directed Auxin Biosynthesis and Root Growth in Arabidopsis
Wenrong He et al.
PLANT CELL (2011)
Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine
Kathleen S. Alexander et al.
PSYCHOPHARMACOLOGY (2011)
Administration of kynurenine during adolescence, but not during adulthood, impairs social behavior in rats
Katelyn V. Trecartin et al.
SCHIZOPHRENIA RESEARCH (2011)
Evaluation of indoleamine 2,3-dioxygenase expression and kynurenine pathway metabolites levels in serum samples of diabetic retinopathy patients
Praveen Kumar Munipally et al.
ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY (2011)
Kynurenine pathway - a new link between endothelial dysfunction and carotid atherosclerosis in chronic kidney disease patients
K. Pawlak et al.
ADVANCES IN MEDICAL SCIENCES (2010)
Structure, expression, and function of kynurenine aminotransferases in human and rodent brains
Qian Han et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2010)
Relationship between an increased serum kynurenine/tryptophan ratio and atherosclerotic parameters in hemodialysis patients
Akihiko Kato et al.
HEMODIALYSIS INTERNATIONAL (2010)
An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells
Joshua D. Mezrich et al.
JOURNAL OF IMMUNOLOGY (2010)
Hydroxyamidine Inhibitors of Indoleamine-2,3-dioxygenase Potently Suppress Systemic Tryptophan Catabolism and the Growth of IDO-Expressing Tumors
Holly K. Koblish et al.
MOLECULAR CANCER THERAPEUTICS (2010)
Kynurenine is an endothelium-derived relaxing factor produced during inflammation
Yutang Wang et al.
NATURE MEDICINE (2010)
Kynurenic Acid Is a Potent Endogenous Aryl Hydrocarbon Receptor Ligand that Synergistically Induces Interleukin-6 in the Presence of Inflammatory Signaling
Brett C. DiNatale et al.
TOXICOLOGICAL SCIENCES (2010)
Presence of kynurenic acid in food and honeybee products
Michal P. Turski et al.
AMINO ACIDS (2009)
Indoleamine 2,3 Dioxygenase-Mediated Tryptophan Catabolism Regulates Accumulation of Th1/Th17 Cells in the Joint in Collagen-Induced Arthritis
Gabriel Criado et al.
ARTHRITIS AND RHEUMATISM (2009)
L-kynurenine treatment alters contextual fear conditioning and context discrimination but not cue-specific fear conditioning
Amy C. Chess et al.
BEHAVIOURAL BRAIN RESEARCH (2009)
Anti-infectious Activity of Tryptophan Metabolites in the L-Tryptophan-L-Kynurenine Pathway
Koji Narui et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2009)
Abnormal red body coloration of the silkworm, Bombyx mori, is caused by a mutation in a novel kynureninase
Yan Meng et al.
GENES TO CELLS (2009)
Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway
Helen J. Ball et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2009)
Plasma tryptophan, kynurenine and 3-hydroxykynurenine measurement using automated on-line solid-phase extraction HPLC-tandem mass spectrometry
Wilhelmina H. A. de Jong et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2009)
Cacao extracts suppress tryptophan degradation of mitogen-stimulated peripheral blood mononuclear cells
M. Jenny et al.
JOURNAL OF ETHNOPHARMACOLOGY (2009)
Age and circadian influences on picolinic acid concentrations in human cerebrospinal fluid
Sarah E. Coggan et al.
JOURNAL OF NEUROCHEMISTRY (2009)
The paradoxical patterns of expression of indoleamine 2,3-dioxygenase in colon cancer
Yan-Fang Gao et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2009)
Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice
J. C. O'Connor et al.
MOLECULAR PSYCHIATRY (2009)
Indoleamine 2,3-dioxygenase activity of acute myeloid leukemia cells can be measured from patients' sera by HPLC and is inducible by IFN-γ
Selim Corm et al.
LEUKEMIA RESEARCH (2009)
Localization of indoleamine 2,3-dioxygenase in human esophageal squamous cell carcinomas
Jinzhong Liu et al.
VIRCHOWS ARCHIV (2009)
Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice
Masaaki Kanai et al.
MOLECULAR BRAIN (2009)
High expression of indoleamine 2,3-dioxygenase gene in prostate cancer
Chantal Feder-Mengus et al.
EUROPEAN JOURNAL OF CANCER (2008)
High-affinity uptake of kynurenine and nitric oxide-mediated inhibition of indoleamine 2,3-dioxygenase in bone marrow-derived myeloid dendritic cells
Toshiaki Hara et al.
IMMUNOLOGY LETTERS (2008)
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease
Luigina Romani et al.
NATURE (2008)
IDO expression in the brain: a double-edged sword
Erik Kwidzinski et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2007)
Effect of Kidney-replenishing herb on the indoleamine 2,3-dioxygenase of human syncytiotrophoblasts cultured in vitro and the balance of helper T-cell cytokines
Xuelian Li et al.
GYNECOLOGICAL ENDOCRINOLOGY (2007)
Nanosensor detection of an immunoregulatory tryptophan influx/kynurenine efflux cycle
Thijs Kaper et al.
PLOS BIOLOGY (2007)
Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan
Richard Metz et al.
CANCER RESEARCH (2007)
Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice
Helen J. Ball et al.
GENE (2007)
Two distinct pathways supply anthranilate as a precursor of the Pseudomonas quinolone signal
John M. Farrow et al.
JOURNAL OF BACTERIOLOGY (2007)
Elevations of endogenous kynurenic acid produce spatial working memory deficits
Amy C. Chess et al.
SCHIZOPHRENIA BULLETIN (2007)
Xanthurenic aciduria due to a mutation in KYNU encoding kynureninase
M. Christensen et al.
JOURNAL OF INHERITED METABOLIC DISEASE (2007)
Crystal structure and mechanism of tryptophan 2,3-dioxygenase, a heme enzyme involved in tryptophan catabolism and in quinolinate biosynthesis
Yang Zhang et al.
BIOCHEMISTRY (2007)
Tryptophan metabolism and indoleamine 2,3-dioxygenase expression in coeliac disease
M. I. Torres et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2007)
Early steps in the biosynthesis of NAD in Arabidopsis start with aspartate and occur in the plastid
Akira Katoh et al.
PLANT PHYSIOLOGY (2006)
Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer:: Effect on tumor-infiltrating T cells
G Brandacher et al.
CLINICAL CANCER RESEARCH (2006)
Biochemical and medical aspects of the indoleamine 2,3-dioxygenase-initiated L-tryptophan metabolism
O Takikawa
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Preliminary array analysis reveals novel genes regulated by ovarian steroids in the monkey raphe region
AP Reddy et al.
PSYCHOPHARMACOLOGY (2005)
Studying the immunosuppressive role of indoleamine 2,3-dioxygenase: tryptophan metabolites suppress rat allogeneic T-cell responses in vitro and in vivo
TM Bauer et al.
TRANSPLANT INTERNATIONAL (2005)
Molecular biology of pyridine nucleotide and nicotine biosynthesis
A Katoh et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2004)
Indoleamine 2,3-dioxygenase expression is restricted to fetal trophoblast giant cells during murine gestation and is maternal genome specific
B Baban et al.
JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2004)
Association of tryptophan 2,3 dioxygenase gene polymorphism with autism
R Nabi et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2004)
Characteristic expression of aryl hydrocarbon receptor repressor gene in human tissues: Organ-specific distribution and variable induction patterns in mononuclear cells
J Yamamoto et al.
LIFE SCIENCES (2004)
Biochemical and phenotypic abnormalities in kynurenine aminotransferase II-deficient mice
P Yu et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Gene expression of enzymes for tryptophan degradation pathway is upregulated in the skin lesions of patients with atopic dermatitis or psoriasis
M Ito et al.
JOURNAL OF DERMATOLOGICAL SCIENCE (2004)
Overexpression of indoleamine 2,3-dioxygenase in human inflammatory bowel disease
AM Wolf et al.
CLINICAL IMMUNOLOGY (2004)
Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase
C Uyttenhove et al.
NATURE MEDICINE (2003)
Effect of systemic administration of L-kynurenine on corticocerebral blood flow under normal and ischemic conditions of the brain in conscious rabbits
K Sas et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2003)
Kynurenate production by cultured human astrocytes
C Kiss et al.
JOURNAL OF NEURAL TRANSMISSION (2003)
Purine, kynurenine, neopterin and lipid peroxidation levels in inflammatory bowel disease
CM Forrest et al.
JOURNAL OF BIOMEDICAL SCIENCE (2002)
Effects of systemic and central nervous system localized inflammation on the contributions of metabolic precursors to the L-kynurenine and quinolinic acid pools in brain
T Kita et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Kynureninase is a novel candidate gene for hypertension in spontaneously hypertensive rats
K Mizutani et al.
HYPERTENSION RESEARCH (2002)
Comparison of the role of dopamine, serotonin, and noradrenaline genes in ADHD, ODD and conduct disorder: multivariate regression analysis of 20 genes
DE Comings et al.
CLINICAL GENETICS (2000)
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