相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Photoinduced cross-linking of formulation buffer amino acids to monoclonal antibodies
Thomas Powell et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2021)
Characterization of Native Reversible Self-Association of a Monoclonal Antibody Mediated by Fab-Fab Interaction
Lorenzo Gentiluomo et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2020)
Discovery of a Photoinduced Histidine-Histidine Cross-Link in an IgG4 Antibody
Thomas Powell et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2020)
Deamidation and isomerization liability analysis of 131 clinical-stage antibodies
Xiaojun Lu et al.
MABS (2019)
Spontaneous cross-linking of proteins at aspartate and asparagine residues is mediated via a succinimide intermediate
Michael G. Friedrich et al.
BIOCHEMICAL JOURNAL (2018)
Protein aggregation - Mechanisms, detection, and control
Wei Wang et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2018)
Cross-linking mass spectrometry: methods and applications in structural, molecular and systems biology
Francis J. O'Reilly et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
A Retrospective Evaluation of the Use of Mass Spectrometry in FDA Biologics License Applications
Sarah Rogstad et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2017)
Forced degradation of recombinant monoclonal antibodies: A practical guide
Christine Nowak et al.
MABS (2017)
Evidence for intermolecular domain exchange in the Fab domains of dimer and oligomers of an IgG1 monoclonal antibody
Yin Luo et al.
MABS (2017)
Discovery and Characterization of Histidine Oxidation Initiated Cross-links in an IgG1 Monoclonal Antibody
Chong-Feng Xu et al.
ANALYTICAL CHEMISTRY (2017)
Mass Spectrometry Approaches for Identification and Quantitation of Therapeutic Monoclonal Antibodies in the Clinical Laboratory
Paula M. Ladwig et al.
CLINICAL AND VACCINE IMMUNOLOGY (2017)
Characterization of mAb dimers reveals predominant dimer forms common in therapeutic mAbs
Friederike Plath et al.
MABS (2016)
Acid-induced aggregation propensity of nivolumab is dependent on the Fc
Boning Liu et al.
MABS (2016)
Charge-mediated Fab-Fc interactions in an IgG1 antibody induce reversible self-association, cluster formation, and elevated viscosity
Jayant Arora et al.
MABS (2016)
Public biotech in 2015-the numbers
Chris Morrison et al.
NATURE BIOTECHNOLOGY (2016)
Discovery and Characterization of a Photo-Oxidative Histidine-Histidine Cross-Link in IgG1 Antibody Utilizing 18O-Labeling and Mass Spectrometry
Min Liu et al.
ANALYTICAL CHEMISTRY (2014)
Protein aggregation and its impact on product quality
Christopher J. Roberts
CURRENT OPINION IN BIOTECHNOLOGY (2014)
Intermolecular interactions and conformation of antibody dimers present in IgG1 biopharmaceuticals
Takafumi Iwura et al.
JOURNAL OF BIOCHEMISTRY (2014)
Structural Characterization of IgG1 mAb Aggregates and Particles Generated Under Various Stress Conditions
Srivalli N. Telikepalli et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2014)
Discovery of Undefined Protein Cross-Linking Chemistry: A Comprehensive Methodology Utilizing 18O-Labeling and Mass Spectrometry
Min Liu et al.
ANALYTICAL CHEMISTRY (2013)
The safety of therapeutic monoclonal antibodies: Implications for cardiovascular disease and targeting the PCSK9 pathway
A. L. Catapano et al.
ATHEROSCLEROSIS (2013)
High-resolution MS for structural characterization of protein therapeutics: advances and future directions
Hui Wei et al.
BIOANALYSIS (2013)
Engineering Aggregation-Resistant Antibodies
Joseph M. Perchiacca et al.
ANNUAL REVIEW OF CHEMICAL AND BIOMOLECULAR ENGINEERING, VOL 3 (2012)
Aggregates in Monoclonal Antibody Manufacturing Processes
Maria Vazquez-Rey et al.
BIOTECHNOLOGY AND BIOENGINEERING (2011)
Fc domain mediated self-association of an IgG1 monoclonal antibody under a low ionic strength condition
Hirotaka Nishi et al.
JOURNAL OF BIOSCIENCE AND BIOENGINEERING (2011)
Salt bridges: Geometrically specific, designable interactions
Jason E. Donald et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2011)
Intramolecular isopeptide bonds: protein crosslinks built for stress?
Hae Joo Kang et al.
TRENDS IN BIOCHEMICAL SCIENCES (2011)
NMR Spectroscopic and Theoretical Analysis of a Spontaneously Formed Lys-Asp Isopeptide Bond
Robert M. Hagan et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)
Increased aggregation propensity of IgG2 subclass over IgG1: Role of conformational changes and covalent character in isolated aggregates
Heather Franey et al.
PROTEIN SCIENCE (2010)
Conformational Implications of an Inversed pH-Dependent Antibody Aggregation
Natalie Perico et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2009)
Elucidation of Two Major Aggregation Pathways in an IgG2 Antibody
Nicholas Van Buren et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2009)
MASS SPECTROMETRY FOR STRUCTURAL CHARACTERIZATION OF THERAPEUTIC ANTIBODIES
Zhongqi Zhang et al.
MASS SPECTROMETRY REVIEWS (2009)
Intra-molecular cross-linking of acidic residues for protein structure studies
Petr Novak et al.
EUROPEAN JOURNAL OF MASS SPECTROMETRY (2008)
Stabilizing isopeptide bonds revealed in Gram-positive bacterial pilus structure
Hae Joo Kang et al.
SCIENCE (2007)
Structural effect of a recombinant monoclonal antibody on hinge region peptide bond hydrolysis
Tao Xiang et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2007)
Formulation considerations for proteins susceptible to asparagine deamidation and aspartate isomerization
Aditya A. Wakankar et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2006)
Protein aggregation and bioprocessing
Mary E. M. Cromwell et al.
AAPS JOURNAL (2006)
Studies on the mechanism of aspartic acid cleavage and glutamine deamidation in the acidic degradation of glucagon
AB Joshi et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2005)
Characterization of a novel modification to monoclonal antibodies: Thioether cross-link of heavy and light chains
GI Tous et al.
ANALYTICAL CHEMISTRY (2005)
Tailor-made antibody therapeutics
PS Chowdhury et al.
METHODS (2005)
Protein stabilization by salt bridges: concepts, experimental approaches and clarification of some misunderstandings
HR Bosshard et al.
JOURNAL OF MOLECULAR RECOGNITION (2004)
分享论文
