期刊
GAIT & POSTURE
卷 46, 期 -, 页码 112-117出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.gaitpost.2016.02.022
关键词
Walking; Aging; iPod; Accelerometer; Partial least square analysis
资金
- Institut Universitaire de France
- French national program 'Programme dInvestissement dAvenir IRT NanoElec [ANR/10AIRT-05]
- Institut Francais des Pays-Bas
Introduction: Normative data of how natural aging affects gait can serve as a frame of reference for changes in gait dynamics due to pathologies. Therefore, the present study aims (1) to identify gait variables sensitive to age-related changes in gait over the adult life span using the iPod and (2) to assess if these variables accurately distinguish young (aged 18-45) from healthy older (aged 46-75) adults. Methods: Trunk accelerations were recorded with an iPod Touch in 59 healthy adults during three minutes of overground walking. Gait variables included gait speed and accelerometry-based gait variables (stride, amplitude, frequency, and trajectory-related variables) in the anterior-posterior (AP) and medio-lateral (ML) directions. Multivariate partial least square analysis (PLS) identified variables sensitive to age-related differences in gait. To classify young and old adults, a PLS-discriminant analysis (PLS-DA) was used to test the accuracy of these variables. Results: The PLS model explained 42% of variation in age. Influential variables were: mean stride time, phase variability index, root mean square, stride variability, AP sample entropy and ML maximal Lyaponov exponent. PLS-DA classified 83% of the participants correctly with a sensitivity of 83% and specificity of 71%. Discussion: Contrary to the frequently reported high gait variability observed in old adults with frailty and fall history, the present study showed that younger compared with older healthy adults had a more variable, less predictable and more symmetrical gait pattern. A model based on a combination of variables reflecting gait dynamics, could distinguish healthy younger adults from older adults. (C) 2016 Elsevier B.V. All rights reserved.
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