Extensive Perivillous Fibrin and Intervillous Histiocytosis in a SARS-CoV-2 Infected Placenta From an Uninfected Newborn: A Case Report Including Immunohistochemical Profiling

Article Virology

Placental SARS-CoV-2 in a pregnant woman with mild COVID-19 disease

Albert L. Hsu et al.

Summary: A case study reported placental infection of SARS-CoV-2 in a patient with mild COVID-19 symptoms, raising concerns about placental vascular pathology and potential vertical transmission. Despite mild infection during pregnancy, there may be risks of placental vasculopathy and viral transmission across the placenta.

JOURNAL OF MEDICAL VIROLOGY (2021)

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Article Medical Laboratory Technology

Chronic Histiocytic Intervillositis With Trophoblast Necrosis Is a Risk Factor Associated With Placental Infection From Coronavirus Disease 2019 (COVID-19) and Intrauterine Maternal-Fetal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission in Live-Born and Stillborn Infants

David A. Schwartz et al.

Summary: The placental pathology findings in newborns infected by transplacental transmission of SARS-CoV-2 revealed chronic histiocytic intervillositis and syncytiotrophoblast necrosis in all placentas. These findings may serve as a pathology risk factor for fetal infection in newborns infected before delivery.

ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE (2021)

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Review Developmental Biology

SARS-CoV-2 placentitis: An uncommon complication of maternal COVID-19

Laura Linehan et al.

Summary: SARS-CoV-2 infection during pregnancy can lead to placental infection, posing a threat to the fetus, though this situation is relatively rare.

PLACENTA (2021)

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Article Pathology