期刊
PARKINSONISM & RELATED DISORDERS
卷 89, 期 -, 页码 148-150出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.parkreldis.2021.07.017
关键词
Parkinson's disease; Deep brain stimulation; Electroencephalogram; Phase amplitude coupling
资金
- Research Committee of CNS Degenerative Diseases, Research on Policy Planning and Evaluation for Rare and Intractable Diseases, Health, Labour and Welfare Sciences Research Grants, the Ministry of Health, Labour and Welfare, Japan [20FC1049]
Our study found a significant reduction in beta-gamma phase amplitude coupling (PAC) values after chronic deep brain stimulation (DBS) in patients with Parkinson's disease, indicating that this reduction is a chronic effect of DBS and not just a transient phenomenon after the start of stimulation.
We compared beta-gamma phase amplitude coupling (PAC) before and one year after chronic deep brain stimulation (DBS) in patients with Parkinson's disease using EEG and observed significant post-operative reduction of PAC values. Our findings suggest that the reduction in PAC due to DBS can be observed after chronic stimulation, which is not a transient phenomenon just after the start of DBS.
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