4.6 Article

Effects of insemination and blood-feeding on locomotor activity of wild-derived females of the malaria mosquito Anopheles coluzzii

期刊

PARASITES & VECTORS
卷 14, 期 1, 页码 -

出版社

BMC
DOI: 10.1186/s13071-021-04967-0

关键词

Anopheles coluzzii; Field; Locomotor activity; Daily rhythms; Insemination; Blood and glucose intakes; Diversity; Chronotypes; Burkina Faso; Residual malaria transmission

资金

  1. Grant ANR Anorhythm by French Agence Nationale de la Recherche [ANR-16-CE35-0008]
  2. Islamic Development Bank
  3. Agro Paris Tech
  4. Agence Nationale de la Recherche (ANR) [ANR-16-CE35-0008] Funding Source: Agence Nationale de la Recherche (ANR)

向作者/读者索取更多资源

This study investigated the behavioural activity changes of Anopheles coluzzii mosquitoes in different physiological states, revealing that insemination and blood digestion status can influence the rhythmic features of locomotor activity. In dim light conditions, inseminated females may exhibit sustained activity during the daytime, potentially impacting residual transmission of malarial parasites.
Background: Behavioural shifts in the canonical location and timing of biting have been reported in natural populations of anopheline malaria vectors following the implementation of insecticide-based indoor vector control interventions. These modifications increase the likelihood of human-vector contact and allow mosquitoes to avoid insecticides, both conditions being favourable to residual transmission of the malarial parasites. The biting behaviour of mosquitoes follows rhythms that are under the control of biological clocks and environmental conditions, modulated by physiological states. In this work we explore modifications of spontaneous locomotor activity expressed by mosquitoes in different physiological states to highlight phenotypic variability associated to circadian control that may contribute to explain residual transmission in the field. Methods: The F-10 generation progeny of field-collected Anopheles coluzzii from southwestern Burkina Faso was tested using an automated recording apparatus (Locomotor Activity Monitor, TriKinetics Inc.) under LD 12:12 or DD light regimens in laboratory-controlled conditions. Activity recordings of each test were carried out for a week with 6-day-old females belonging to four experimental treatments, representing factorial combinations of two physiological variables: insemination status (virgin vs inseminated) and gonotrophic status (glucose fed vs blood fed). Chronobiological features of rhythmicity in locomotor activity were explored using periodograms, diversity indices, and generalized linear mixed modelling. Results: The average strength of activity, onset of activity, and acrophase were modulated by both nutritional and insemination status as well as by the light regimen. Inseminated females showed a significant excess of arrhythmic activity under DD. When rhythmicity was observed in DD, females displayed sustained activity also during the subjective day. Conclusions: Insemination and gonotrophic status influence the underlying light and circadian control of chronobiological features of locomotor activity. Overrepresentation of arrhythmic chronotypes as well as the sustained activity of inseminated females during the subjective day under DD conditions suggests potential activity of natural populations of A. coluzzii during daytime under dim conditions, with implications for residual transmission of malarial parasites.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据