期刊
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
卷 44, 期 10, 页码 1724-1732出版社
WILEY
DOI: 10.1111/pace.14347
关键词
ablation; age; atrial Fibrillation; trigger foci
资金
- Taipei Veterans General Hospital grant [V107C-041, VGHUST107-G1-7-1, V108C-055]
- [MOST 106-2314-B-010-035-MY3]
- [106-2634-F-075-001]
Young AF patients have a higher incidence of only non-PV foci, mostly located in the SVC, compared to middle-aged and old patients. While the LA mean voltage was higher and the very late recurrence rate after AF ablation was lower in the young group, final AF recurrence rates and complication rates were similar among all age groups after a mean follow-up of 5.6 years.
Background Atrial fibrillation (AF) prevalence increases with age. Aging affects the substrate properties of the left atrium (LA) and the outcomes of catheter ablation for treating AF. We investigated the AF trigger distribution and catheter ablation outcomes in patients of different ages with AF. Methods 1585 patients with AF (1181 paroxysmal and 404 non- paroxysmal AF) who had undergone catheter ablation were enrolled. The patients were divided into young (20-40 year-old, n = 175), middle-aged (41-64 year-old, n = 1134), and old (>= 65 year-old, n = 276) groups. Electrophysiological characteristics and AF trigger sites were recorded. Result The incidence of AF with only non-pulmonary vein (non-PV) foci was higher in the young group than in the other groups (8.6% vs. 3.6% vs. 3.3%, p < 0.01). Non-PV foci were more commonly located in the superior vena cava (SVC) in the young group than in the other groups (13.1% vs. 7.8% vs. 6.5%, p = 0.03). The left atrium (LA) mean voltage was higher and the incidence of very late recurrence after AF ablation was lower in the young group than in the other groups. However, the final AF recurrence rate after multiple procedures and complication rates were similar among all the groups at a mean follow-up of 5.6 years. Conclusion The young patients with AF had a higher incidence of only non-PV foci, mostly located in SVC, than the middle-aged and old patients. Our study highlights the importance of identifying the non-PV foci in catheter ablation of young patients with AF.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据