相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Crystal structure of the catalytic subunit of bovine pyruvate dehydrogenase phosphatase
Youzhong Guo et al.
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS (2020)
Oleanolic Acid Decreases IL-1β-Induced Activation of Fibroblast-Like Synoviocytes via the SIRT3-NF-κB Axis in Osteoarthritis
Jiapeng Bao et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2020)
Pyruvate dehydrogenase kinase 1 interferes with glucose metabolism reprogramming and mitochondrial quality control to aggravate stress damage in cancer
Xinyue Deng et al.
JOURNAL OF CANCER (2020)
Tumor-initiating cells establish an IL-33-TGF-β niche signaling loop to promote cancer progression
Sachiko Taniguchi et al.
SCIENCE (2020)
Dichloroacetate enhances the antitumor effect of pirarubicin via regulating the ROS-JNK signaling pathway in liver cancer cells
Xiao-Jing Yan et al.
CANCER DRUG RESISTANCE (2020)
NRF2 activation promotes the recurrence of dormant tumour cells through regulation of redox and nucleotide metabolism
Douglas B. Fox et al.
NATURE METABOLISM (2020)
Modulating NRF2 in Disease: Timing Is Everything
Matthew Dodson et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 59 (2019)
Understanding of ROS-Inducing Strategy in Anticancer Therapy
Su Ji Kim et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)
Identification of novel indole derivatives acting as inhibitors of the Keap1-Nrf2 interaction
Barbara Cosimelli et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2019)
Non-covalent NRF2 Activation Confers Greater Cellular Protection than Covalent Activation
Pengfei Liu et al.
CELL CHEMICAL BIOLOGY (2019)
Glycolysis gatekeeper PDK1 reprograms breast cancer stem cells under hypoxia
F. Peng et al.
ONCOGENE (2018)
Reversal of the Warburg effect with DCA in PDGF-treated human PASMC is potentiated by pyruvate dehydrogenase kinase-1 inhibition mediated through blocking Akt/GSK-3β signalling
Bingbing Li et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2018)
Targeted production of reactive oxygen species in mitochondria to overcome cancer drug resistance
Hai Wang et al.
NATURE COMMUNICATIONS (2018)
Targeting SLC25A10 alleviates improved antioxidant capacity and associated radioresistance of cancer cells induced by chronic-cycling hypoxia
Julian Hlouschek et al.
CANCER LETTERS (2018)
A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signalling
Michael J. Bollong et al.
NATURE (2018)
Biochemical and clinical relevance of alpha lipoic acid: antioxidant and anti-inflammatory activity, molecular pathways and therapeutic potential
Daniele Tibullo et al.
INFLAMMATION RESEARCH (2017)
Dicumarol inhibits PDK1 and targets multiple malignant behaviors of ovarian cancer cells
Wenjia Zhang et al.
PLOS ONE (2017)
Suppression of a cancer stem-like phenotype mediated by alpha-lipoic acid in human lung cancer cells through down-regulation of β-catenin and Oct-4
Preeyaporn Plaimee Phiboonchaiyanan et al.
CELLULAR ONCOLOGY (2017)
Correction: KEAP1 loss modulates sensitivity to kinase targeted therapy in lung cancer
Elsa Beyer Krall et al.
eLife (2017)
Nuclear Factor-Erythroid-2-Related Factor 2 in Aging and Lung Fibrosis
Shobha M. Swamy et al.
AMERICAN JOURNAL OF PATHOLOGY (2016)
The disulfide compound α-lipoic acid and its derivatives: A novel class of anticancer agents targeting mitochondria
Bastian Doersam et al.
CANCER LETTERS (2016)
PI3Kγ is a molecular switch that controls immune suppression
Megan M. Kaneda et al.
NATURE (2016)
AMPK/p53 Axis Is Essential for α-Lipoic Acid-Regulated Metastasis in Human and Mouse Colon Cancer Cells
Sunmi Park et al.
JOURNAL OF INVESTIGATIVE MEDICINE (2015)
Diagnosis, prognosis, and prediction of non-small cell lung cancer. Importance of morphology, immunohistochemistry and molecular pathology
A. Warth
PATHOLOGE (2015)
α-Lipoic acid protects kidney from oxidative stress and mitochondrial dysfunction associated to inflammatory conditions
Maria Cecilia Cimolai et al.
FOOD & FUNCTION (2014)
A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence
Joanna Kaplon et al.
NATURE (2013)
SnapShot: Non-Small Cell Lung Cancer
Rebecca S. Heist et al.
CANCER CELL (2012)
Oxidative stress, inflammation, and cancer How are they linked?
Simone Reuter et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
Dunyaporn Trachootham et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
The effects and mechanisms of mitochondrial nutrient alpha-lipoic acid on improving age-associated mitochondrial and cognitive dysfunction: An overview
Jiankang Liu
NEUROCHEMICAL RESEARCH (2008)
Phosphorylation of serine 264 impedes active site accessibility in the E1 component of the human pyruvate dehydrogenase multienzyme complex
Franziska Seifert et al.
BIOCHEMISTRY (2007)
Reactive oxygen species mediate caspase activation and apoptosis induced by lipoic acid in human lung epithelial cancer cells through Bcl-2 down-regulation
Jirapan Moungjaroen et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Superoxide dismutase as a target for the selective killing of cancer cells
P Huang et al.
NATURE (2000)