Central Nervous System Cell-Derived Exosomes in Neurodegenerative Diseases

Exosomes are a type of extracellular vesicles secreted by almost all kinds of mammalian cells that shuttle cargo from one cell to another, indicative of its role in cell-to-cell transportation. Interestingly, exosomes are known to undergo alterations or serve as a pathway in multiple diseases, including neurodegenerative diseases. In the central nervous system (CNS), exosomes originating from neurons or glia cells contribute to or inhibit the progression of CNS-related diseases in special ways. In lieu of this, the current study investigated the effect of CNS cell-derived exosomes on different neurodegenerative diseases.

Automated summary

Exosomes, secreted by mammalian cells, play a role in cell-to-cell transportation and are involved in various diseases, including neurodegenerative diseases. In the central nervous system, exosomes from neurons or glia cells have unique effects on CNS-related diseases.