Rupture-Like Shrinkage and Regrowth of Endolymphatic Hydrops in Meniere's Disease During Remission

Objective: To clarify pathophysiological characteristics of Meniere's disease during the remission phase. Patients: Two Meniere's disease patients with different disease durations, whose endolymphatic hydrops was longitudinally observed using 3-T magnetic resonance imaging. Interventions: Diagnostic. Main Outcomes and Measures: Morphological changes of endolymphatic hydrops visualized using 3-T magnetic resonance imaging. Results: Rupture-like shrinkage and regrowth of endolymphatic hydrops during the remission phase was observed in both patients. Conclusion: The remission phase with hearing improvement could be as important as vertigo attacks in Meniere's disease.

Automated summary

This study observed longitudinal changes in endolymphatic hydrops of Meniere's disease patients during the remission phase using 3-T magnetic resonance imaging. The results showed rupture-like shrinkage and regrowth of endolymphatic hydrops in both patients. The conclusion suggests that the remission phase with hearing improvement may be as important as vertigo attacks in Meniere's disease.