期刊
ORGANIC LETTERS
卷 23, 期 19, 页码 7508-7512出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.1c02733
关键词
-
资金
- Foundation for Polish Science [TEAM/2016-3/24]
- National Science Centre [2020/38/A/ST4/00597, 2019/03/X/ST4/01147]
Three Atropisomers of Blatter radicals were synthesized and separated by chiral high-performance liquid chromatography. Their absolute configurations were determined through experimental and computational methods. Further analysis revealed the presence of intramolecular pi-pi interactions in the radicals.
Atropisomers of three Blatter radicals were obtained by the addition of 8-substituted 1-naphthyllithiums to 3-phenyl and 3-t-butylbenzo[e][1,2,4]triazine and separated by chiral high-performance liquid chromatography. Their absolute configurations were assigned by a comparison of experimental and timedependent density functional theory calculated electronic circular dichroism spectra. The free energy of activation, Delta G(298)(double dagger), and the half life of racemization, t(1/2), at 298 K were determined at similar to 25 kcal mol(-1) and <130 h, respectively. Intramolecular pi-pi interactions in radicals were evident from single-crystal X-ray diffraction, density functional theory, and electrochemical analyses.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据