期刊
NUTRITIONAL NEUROSCIENCE
卷 25, 期 11, 页码 2239-2246出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/1028415X.2021.1954291
关键词
Dietary phytochemical index; DPI; diet quality; stroke; case-control; epidemiologic study; dietry intakes; food frequency questionnaire
资金
- Isfahan University of Medical Sciences
- Islamic Republic of Iran [187028 IUMS]
- School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
The study found evidence of a significant inverse association between dietary phytochemical index (DPI) and the odds of stroke in adults, with individuals in the highest DPI tertile having a lower risk of stroke. Further prospective studies are needed to confirm this association.
Background & aim No study explores the association of dietary phytochemical index (DPI) with stroke. This study was undertaken to obtain the required insight in this regard in Iranian adults. Methods This hospital-based case-control study was carried out on 195 stroke patients (diagnosed based on clinical and brained CT findings) and 195 control subjects with no history of cerebrovascular diseases or neurologic disorders). Data collection on dietary intakes was done using a 168-item validated FFQ. DPI was calculated using the McCarty equation. Logistic regression model in different models was used to evaluate the association between DPI and stroke. Results Mean age of study participants was 64.8 years, and 53.4% of them were male. Individuals in the highest tertile of DPI were younger (63 +/- 11 vs. 67.4 +/- 13 y, P = 0.01) and less likely to be physically active (2804 +/- 5714 vs. 4772 +/- 11912 M, P = 0.03). After adjustment for potential confounders, no significant relationship was observed between DPI and stroke risk (OR: 0.76; 95% CI: 0.39-1.49). However, when we considered the effect of dietary intakes, subjects in the top tertile of DPI were 61% less likely to have a stroke than those in the bottom tertile (OR: 0.39; 95% CI: 0.16-0.95). When BMI was controlled, the association between DPI and stroke became strengthened (OR: 0.32; 95% CI: 0.12-0.86). Conclusion We found evidence indicating a significant inverse association between DPI and odds of stroke in adults. Further prospective studies are warranted to confirm this association.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据