相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Three-Dimensional Structure of RNA Monomeric G-Quadruplex Containing ALS and FTD Related G4C2 Repeat and Its Binding with TMPyP4 Probed by Homology Modeling based on Experimental Constraints and Molecular Dynamics Simulations
Kelly Mulholland et al.
ACS CHEMICAL NEUROSCIENCE (2020)
Systematic investigation of sequence requirements for DNA i-motif formation
Petra Skolakova et al.
NUCLEIC ACIDS RESEARCH (2019)
Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD
Lindsey D. Goodman et al.
NATURE NEUROSCIENCE (2019)
A chair-type G-quadruplex structure formed by a human telomeric variant DNA in K+ solution
Changdong Liu et al.
CHEMICAL SCIENCE (2019)
I-motif DNA structures are formed in the nuclei of human cells
Mahdi Zeraati et al.
NATURE CHEMISTRY (2018)
Characterizations of distinct parallel and antiparallel G-quadruplexes formed by two-repeat ALS and FTD related GGGGCC sequence
Bo Zhou et al.
SCIENTIFIC REPORTS (2018)
C9orf72-mediated ALS and FTD: multiple pathways to disease
Rubika Balendra et al.
NATURE REVIEWS NEUROLOGY (2018)
High-resolution DNA quadruplex structure containing all the A-, G-, C-, T-tetrads
Hehua Liu et al.
NUCLEIC ACIDS RESEARCH (2018)
G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo
Roberto Simone et al.
EMBO MOLECULAR MEDICINE (2018)
Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene
Xinmei Wen et al.
NEUROSCIENCE LETTERS (2017)
An amyloid-like cascade hypothesis for C9orf72 ALS/FTD
Dieter Edbauer et al.
CURRENT OPINION IN NEUROBIOLOGY (2016)
Structural insight into C9orf72 hexanucleotide repeat expansions: Towards new therapeutic targets in FTD-ALS
Vijay Kumar et al.
NEUROCHEMISTRY INTERNATIONAL (2016)
A novel transition pathway of ligand-induced topological conversion from hybrid forms to parallel forms of human telomeric G-quadruplexes
Zi-Fu Wang et al.
NUCLEIC ACIDS RESEARCH (2016)
Metal Cations in G-Quadruplex Folding and Stability
Debmalya Bhattacharyya et al.
FRONTIERS IN CHEMISTRY (2016)
G-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptome
Roberto Simone et al.
FEBS LETTERS (2015)
Characterization of DNA G-quadruplex species forming from C9ORF72 G4C2-expanded repeats associated with amyotrophic lateral sclerosis and frontotemporal lobar degeneration
Primoz Sket et al.
NEUROBIOLOGY OF AGING (2015)
Solution structure of a DNA quadruplex containing ALS and FTD related GGGGCC repeat stabilized by 8-bromodeoxyguanosine substitution
Jasna Brcic et al.
NUCLEIC ACIDS RESEARCH (2015)
Topology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD
Bo Zhou et al.
SCIENTIFIC REPORTS (2015)
Small-molecule quadruplex-targeted drug discovery
Stephan A. Ohnmacht et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)
C9orf72 nucleotide repeat structures initiate molecular cascades of disease
Aaron R. Haeusler et al.
NATURE (2014)
Unconventional features of C9ORF72 expanded repeat in amyotrophic lateral sclerosis and frontotemporal lobar degeneration
Sabina Vatovec et al.
NEUROBIOLOGY OF AGING (2014)
Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS
Zhaoming Su et al.
NEURON (2014)
Crystal structure of a DNA/Ba2+ G-quadruplex containing a water-mediated C-tetrad
Diana Zhang et al.
NUCLEIC ACIDS RESEARCH (2014)
The Disease-associated r(GGGGCC)n Repeat from the C9orf72 Gene Forms Tract Length-dependent Uni- and Multimolecular RNA G-quadruplex Structures
Kaalak Reddy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study
Elisa Majounie et al.
LANCET NEUROLOGY (2012)
DNA secondary structures: stability and function of G-quadruplex structures
Matthew L. Bochman et al.
NATURE REVIEWS GENETICS (2012)
C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes
Pietro Fratta et al.
SCIENTIFIC REPORTS (2012)
REFMAC5 for the refinement of macromolecular crystal structures
Garib N. Murshudov et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2011)
Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
Mariely DeJesus-Hernandez et al.
NEURON (2011)
A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
Alan E. Renton et al.
NEURON (2011)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Paul D. Adams et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
Frontotemporal dementia and motor neurone disease: Overlapping clinic-pathological disorders
Patricia Lillo et al.
JOURNAL OF CLINICAL NEUROSCIENCE (2009)
Four-stranded nucleic acids: structure, function and targeting of G-quadruplexes
Julian Leon Huppert
CHEMICAL SOCIETY REVIEWS (2008)
A short history of SHELX
George M. Sheldrick
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES (2008)
Phaser crystallographic software
Airlie J. McCoy et al.
JOURNAL OF APPLIED CRYSTALLOGRAPHY (2007)
Quadruplex DNA: sequence, topology and structure
Sarah Burge et al.
NUCLEIC ACIDS RESEARCH (2006)
HKL-3000:: the integration of data reduction and structure solution -: from diffraction images to an initial model in minutes
Wladek Minor et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2006)
Crystal structure of parallel quadruplexes from human telomeric DNA
GN Parkinson et al.
NATURE (2002)
Cation-directed self-assembly of lipophilic nucleosides: the cation's central role in the structure and dynamics of a hydrogen-bonded assembly
MM Cai et al.
TETRAHEDRON (2002)
Folding of the thrombin aptamer into a G-quadruplex with Sr2+:: Stability, heat, and hydration
BI Kankia et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2001)
Medical progress: Amyotrophic lateral sclerosis.
LP Rowland et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
Effect of divalent cations on antiparallel G-quartet structure of d(G4T4C4)
D Miyoshi et al.
FEBS LETTERS (2001)
Cation-dependent conformational switches in d-TGGCGGC containing two triplet repeats of Fragile X Syndrome: NMR observations
PK Patel et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
NMR observation of a novel C-tetrad in the structure of the SV40 repeat sequence GGGCGG
PK Patel et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Lead is unusually effective in sequence-specific folding of DNA
I Smirnov et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)